pubmed-article:6977595 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6977595 | lifeskim:mentions | umls-concept:C0029347 | lld:lifeskim |
pubmed-article:6977595 | lifeskim:mentions | umls-concept:C1522424 | lld:lifeskim |
pubmed-article:6977595 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
pubmed-article:6977595 | lifeskim:mentions | umls-concept:C0042210 | lld:lifeskim |
pubmed-article:6977595 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
pubmed-article:6977595 | lifeskim:mentions | umls-concept:C1548795 | lld:lifeskim |
pubmed-article:6977595 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:6977595 | pubmed:dateCreated | 1982-5-27 | lld:pubmed |
pubmed-article:6977595 | pubmed:abstractText | Induction of cross-protective immunity against serologically distinct subtypes of influenza A virus in mice was examined in an attempt to correlate cross-protection with heterotypic lymphocyte responses. Live and inactivated virus vaccines protected against the homologous subtype, but only whole virus protected against heterologous subtypes. Live virus vaccines provided better cross-protection than inactivated virus vaccines. A weak defense against heterotypic challenge generated by live H0N1 virus could be boosted by cross-stimulation with whole H3N2 virus and by restimulation with pathogenic H0N1 virus. Heterotypic protection persisted for at least five months. Live viruses induced cross-reactive cytotoxic T cells in normal mice. However, cross-stimulation with heterologous virus was required to generate secondary cytotoxicity. Cross-reactive B lymphocytes were evident after inoculation with whole virus. | lld:pubmed |
pubmed-article:6977595 | pubmed:language | eng | lld:pubmed |
pubmed-article:6977595 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6977595 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:6977595 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6977595 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6977595 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6977595 | pubmed:month | Mar | lld:pubmed |
pubmed-article:6977595 | pubmed:issn | 0022-1899 | lld:pubmed |
pubmed-article:6977595 | pubmed:author | pubmed-author:ArmerdingDD | lld:pubmed |
pubmed-article:6977595 | pubmed:author | pubmed-author:LiehlEE | lld:pubmed |
pubmed-article:6977595 | pubmed:author | pubmed-author:GhazzouliII | lld:pubmed |
pubmed-article:6977595 | pubmed:author | pubmed-author:RossiterHH | lld:pubmed |
pubmed-article:6977595 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6977595 | pubmed:volume | 145 | lld:pubmed |
pubmed-article:6977595 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6977595 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6977595 | pubmed:pagination | 320-30 | lld:pubmed |
pubmed-article:6977595 | pubmed:dateRevised | 2005-11-22 | lld:pubmed |
pubmed-article:6977595 | pubmed:meshHeading | pubmed-meshheading:6977595-... | lld:pubmed |
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pubmed-article:6977595 | pubmed:year | 1982 | lld:pubmed |
pubmed-article:6977595 | pubmed:articleTitle | Evaluation of live and inactivated influenza A virus vaccines in a mouse model. | lld:pubmed |
pubmed-article:6977595 | pubmed:publicationType | Journal Article | lld:pubmed |
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