| pubmed-article:6972150 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6972150 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
| pubmed-article:6972150 | lifeskim:mentions | umls-concept:C0085979 | lld:lifeskim |
| pubmed-article:6972150 | lifeskim:mentions | umls-concept:C0002668 | lld:lifeskim |
| pubmed-article:6972150 | lifeskim:mentions | umls-concept:C0026724 | lld:lifeskim |
| pubmed-article:6972150 | lifeskim:mentions | umls-concept:C0036537 | lld:lifeskim |
| pubmed-article:6972150 | lifeskim:mentions | umls-concept:C0038351 | lld:lifeskim |
| pubmed-article:6972150 | lifeskim:mentions | umls-concept:C0017119 | lld:lifeskim |
| pubmed-article:6972150 | lifeskim:mentions | umls-concept:C0005367 | lld:lifeskim |
| pubmed-article:6972150 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:6972150 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
| pubmed-article:6972150 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:6972150 | pubmed:dateCreated | 1981-7-9 | lld:pubmed |
| pubmed-article:6972150 | pubmed:abstractText | Administration of Ca++ (1.5 mg/kg i.v.) increased the output of both H+ and HCO-3 from the stomach of the anesthetized guinea pig as determined by measurement of gastric intraluminal pH and pCO2. The rise in HC-3 secretion was slightly greater than that in H+, resulting in a decrease in net acidity. Fundic mucosa isolated from frogs was used to study the mechanisms of the stimulatory actions. An increase in Ca++ concentration in the nutrient (serosal) bathing solution from 1.8 to 7.2 mM stimulated H+ transport in this preparation. The effect of raising Ca++ concentration was inhibited by the histamine H2 receptor antagonist Metiamide and by increasing nutrient Mg++. Stimulation of H+ transport, sensitive to Metiamide, was also observed with the calcium ionophore A23187 (4 micrograms/ml, nutrient side). The results indicate that at the mucosal level, Ca++ stimulates H+ transport by release of histamine from mucosal stores with properties similar to those of mast cells. Transport of HCO-3 in isolated mucosae was studied after inhibition of H+ transport my metiamide. An increase in nutrient Ca++ concentration stimulated the HCO-3 transport but the calcium ionophore had no effect. This action of Ca++ was abolished by atropine (10(-6) M) and by raising nutrient Mg++, suggesting that it reflects release of acetylcholine from intramucosal nervous tissue. Thus Ca++ stimulated gastric transport of both H+ and HCO-3 in vivo and in vitro but evidence for a direct action on the transporting (parietal and epithelial) cells was not obtained. | lld:pubmed |
| pubmed-article:6972150 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6972150 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6972150 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6972150 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6972150 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6972150 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6972150 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6972150 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6972150 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6972150 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6972150 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:6972150 | pubmed:issn | 0001-6772 | lld:pubmed |
| pubmed-article:6972150 | pubmed:author | pubmed-author:GarnerAA | lld:pubmed |
| pubmed-article:6972150 | pubmed:author | pubmed-author:FlemströmGG | lld:pubmed |
| pubmed-article:6972150 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6972150 | pubmed:volume | 110 | lld:pubmed |
| pubmed-article:6972150 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6972150 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6972150 | pubmed:pagination | 419-26 | lld:pubmed |
| pubmed-article:6972150 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:meshHeading | pubmed-meshheading:6972150-... | lld:pubmed |
| pubmed-article:6972150 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:6972150 | pubmed:articleTitle | Stimulation of gastric acid and bicarbonate secretions by calcium in guinea pig stomach and amphibian isolated mucosa. | lld:pubmed |
| pubmed-article:6972150 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6972150 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6972150 | lld:pubmed |
