pubmed-article:6935649 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6935649 | lifeskim:mentions | umls-concept:C0026649 | lld:lifeskim |
pubmed-article:6935649 | lifeskim:mentions | umls-concept:C0018787 | lld:lifeskim |
pubmed-article:6935649 | lifeskim:mentions | umls-concept:C1622418 | lld:lifeskim |
pubmed-article:6935649 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
pubmed-article:6935649 | lifeskim:mentions | umls-concept:C1706211 | lld:lifeskim |
pubmed-article:6935649 | lifeskim:mentions | umls-concept:C0678640 | lld:lifeskim |
pubmed-article:6935649 | lifeskim:mentions | umls-concept:C0597484 | lld:lifeskim |
pubmed-article:6935649 | lifeskim:mentions | umls-concept:C0007961 | lld:lifeskim |
pubmed-article:6935649 | lifeskim:mentions | umls-concept:C1546426 | lld:lifeskim |
pubmed-article:6935649 | lifeskim:mentions | umls-concept:C1548280 | lld:lifeskim |
pubmed-article:6935649 | pubmed:issue | 11 | lld:pubmed |
pubmed-article:6935649 | pubmed:dateCreated | 1981-3-24 | lld:pubmed |
pubmed-article:6935649 | pubmed:abstractText | The Na+-Ca2+ exchange was studied in a highly purified vesicular preparation derived from heart sarcolemma. The initial velocity of the Na+-driven Ca2+ influx, which was monitored continuously with a specific electrode, was 15 nmol/mg of protein per sec; the total Ca2+-accumulation capacity was 80 nmol/mg of protein. The Na+-Ca2+ exchange generated a current that was compensated for by the uptake of tetraphenylphosphonium in (Ph4P+) (when the latter was present in the medium), the influx of K+, and the efflux of Cl-. The movements of Ph4P were followed with a specific electrode. Ca2+ in the concentration range 3-50 microM induced an increase in the permeability of the sarcolemmal membrane to K+. Under conditions of optimal charge neutralization by K+ (i.e., in the presence of valinomycin), the Km (Ca2+) of the exchanger was 1.5 microM. The Na+-Ca2+ exchange was inhibited by chlorpromazine and was not inhibited by vanadate. | lld:pubmed |
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pubmed-article:6935649 | pubmed:language | eng | lld:pubmed |
pubmed-article:6935649 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6935649 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:6935649 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6935649 | pubmed:month | Nov | lld:pubmed |
pubmed-article:6935649 | pubmed:issn | 0027-8424 | lld:pubmed |
pubmed-article:6935649 | pubmed:author | pubmed-author:CarafoliEE | lld:pubmed |
pubmed-article:6935649 | pubmed:author | pubmed-author:CaroniPP | lld:pubmed |
pubmed-article:6935649 | pubmed:author | pubmed-author:ReinlibLL | lld:pubmed |
pubmed-article:6935649 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6935649 | pubmed:volume | 77 | lld:pubmed |
pubmed-article:6935649 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6935649 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6935649 | pubmed:pagination | 6354-8 | lld:pubmed |
pubmed-article:6935649 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:6935649 | pubmed:year | 1980 | lld:pubmed |
pubmed-article:6935649 | pubmed:articleTitle | Charge movements during the Na+-Ca2+ exchange in heart sarcolemmal vesicles. | lld:pubmed |
pubmed-article:6935649 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6935649 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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