| pubmed-article:6934533 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6934533 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:6934533 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:6934533 | lifeskim:mentions | umls-concept:C0439855 | lld:lifeskim |
| pubmed-article:6934533 | lifeskim:mentions | umls-concept:C0010366 | lld:lifeskim |
| pubmed-article:6934533 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:6934533 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:6934533 | pubmed:dateCreated | 1981-2-26 | lld:pubmed |
| pubmed-article:6934533 | pubmed:abstractText | The Tcp-1 gene located within the T/t complex on chromosome 17 of the mouse codes for a major cell surface-associated protein p63/6.9. Previously, we identified two structural alleles of this gene which specify alternate forms of the p63/6.9 protein. The Tcp-1b allele is associated with all wild-type chromosome 17; the Tcp-1a allele is found only with chromosome 17 carrying a complete t haplotype. Normal recombination along a major length of chromosome 17 is suppressed in mice that are heterozygous for any complete t haplotype. Suppression is not complete, however, and rare crossing over between wild-type and t haplotype chromatin does occur. In this report, 15 rare recombinant chromosomes have been analyzed for Tcp-1 alleles. The results indicate that in four independent events the Tcp-1b and Tcp-1a alleles have become associated in cis position in a single DNA molecule. Further genetic analysis provides support for the hypothesis that a significant nonhomology exists between the arrangement of DNA sequences on wild-type and t-carrying chromosome 17. This could account for both the suppression of normal recombination along the stretch of t chromatin and the frequent unequal crossing over when rare recombinational events do take place. | lld:pubmed |
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| pubmed-article:6934533 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6934533 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6934533 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6934533 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6934533 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6934533 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:6934533 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:6934533 | pubmed:author | pubmed-author:WhiteMM | lld:pubmed |
| pubmed-article:6934533 | pubmed:author | pubmed-author:ArtztKK | lld:pubmed |
| pubmed-article:6934533 | pubmed:author | pubmed-author:SilverL MLM | lld:pubmed |
| pubmed-article:6934533 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6934533 | pubmed:volume | 77 | lld:pubmed |
| pubmed-article:6934533 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6934533 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6934533 | pubmed:pagination | 6077-80 | lld:pubmed |
| pubmed-article:6934533 | pubmed:dateRevised | 2010-9-13 | lld:pubmed |
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| pubmed-article:6934533 | pubmed:meshHeading | pubmed-meshheading:6934533-... | lld:pubmed |
| pubmed-article:6934533 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:6934533 | pubmed:articleTitle | Evidence for unequal crossing over within the mouse T/t complex. | lld:pubmed |
| pubmed-article:6934533 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6934533 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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