| pubmed-article:6827266 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6827266 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:6827266 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:6827266 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:6827266 | lifeskim:mentions | umls-concept:C2350570 | lld:lifeskim |
| pubmed-article:6827266 | lifeskim:mentions | umls-concept:C0007776 | lld:lifeskim |
| pubmed-article:6827266 | lifeskim:mentions | umls-concept:C0022655 | lld:lifeskim |
| pubmed-article:6827266 | lifeskim:mentions | umls-concept:C0001613 | lld:lifeskim |
| pubmed-article:6827266 | lifeskim:mentions | umls-concept:C0228174 | lld:lifeskim |
| pubmed-article:6827266 | lifeskim:mentions | umls-concept:C0034826 | lld:lifeskim |
| pubmed-article:6827266 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:6827266 | pubmed:dateCreated | 1983-4-7 | lld:pubmed |
| pubmed-article:6827266 | pubmed:abstractText | Microvessels isolated from rat cerebral cortex consist mainly of capillaries (greater than 85%). Fresh, intact microvessel preparations have been analyzed by radioligand binding techniques for muscarinic receptors. Scatchard analysis of specific quinuclidinyl benzilate (QNB) binding indicates that microvessels possess a large number of muscarinic sites (914 fmol/mg protein) of high affinity (KD = 0.034 nM). The association and dissociation rate constants (0.37 min-1 nM-1 and 0.0067 min-1, respectively) yield an equilibrium KD of 0.018 nM. Displacement of [3H]QNB by muscarinic ligands and control substances is typical of muscarinic receptors. The results indicate that cerebral microvessels possess a large population of muscarinic receptors. | lld:pubmed |
| pubmed-article:6827266 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6827266 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6827266 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6827266 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6827266 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6827266 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6827266 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6827266 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6827266 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:6827266 | pubmed:issn | 0022-3042 | lld:pubmed |
| pubmed-article:6827266 | pubmed:author | pubmed-author:WienerJJ | lld:pubmed |
| pubmed-article:6827266 | pubmed:author | pubmed-author:GiacomelliFF | lld:pubmed |
| pubmed-article:6827266 | pubmed:author | pubmed-author:DiglioC ACA | lld:pubmed |
| pubmed-article:6827266 | pubmed:author | pubmed-author:MarksB HBH | lld:pubmed |
| pubmed-article:6827266 | pubmed:author | pubmed-author:GrammasPP | lld:pubmed |
| pubmed-article:6827266 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6827266 | pubmed:volume | 40 | lld:pubmed |
| pubmed-article:6827266 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6827266 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6827266 | pubmed:pagination | 645-51 | lld:pubmed |
| pubmed-article:6827266 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:meshHeading | pubmed-meshheading:6827266-... | lld:pubmed |
| pubmed-article:6827266 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6827266 | pubmed:articleTitle | Identification of muscarinic receptors in rat cerebral cortical microvessels. | lld:pubmed |
| pubmed-article:6827266 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6827266 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6827266 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
