| pubmed-article:6815094 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6815094 | lifeskim:mentions | umls-concept:C0023861 | lld:lifeskim |
| pubmed-article:6815094 | lifeskim:mentions | umls-concept:C0085979 | lld:lifeskim |
| pubmed-article:6815094 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:6815094 | lifeskim:mentions | umls-concept:C0030958 | lld:lifeskim |
| pubmed-article:6815094 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:6815094 | lifeskim:mentions | umls-concept:C1998793 | lld:lifeskim |
| pubmed-article:6815094 | lifeskim:mentions | umls-concept:C1522673 | lld:lifeskim |
| pubmed-article:6815094 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6815094 | pubmed:dateCreated | 1983-1-19 | lld:pubmed |
| pubmed-article:6815094 | pubmed:abstractText | The immunological properties of peptidoglycan (L-PG) purified from the cell wall skeleton (L-CWS) of Listeria monocytogenes strain EGD were investigated and compared with the properties of L-CWS. L-PG consisted of alanine, glutamic acid, alpha, epsilon-diaminopimelic acid, muramic acid, and glucosamine. L-PG showed potent adjuvant activities for circulating antibody formation and development of delayed-type hypersensitivity to bacterial alpha-amylase in vivo and for the primary immune response to sheep erythrocytes in vitro, as well as L-CWS. Both L-PG and L-CWS enhanced the generation of cell-mediated cytotoxicity in allogeneic mice and activated thioglycolate-elicited peritoneal macrophages and macrophage cell line RAW 264 to kill tumor target cells in vitro. We also found that L-PG acted on normal spleen cells as a mitogen. Both L-PG and L-CWS had tumor (Meth A)-suppressive and -regressive activities in syngeneic mice. Our results suggest that the L-PG moiety retains the adjuvant and antitumor activities of L-CWS. | lld:pubmed |
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| pubmed-article:6815094 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6815094 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6815094 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:6815094 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6815094 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:6815094 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:6815094 | pubmed:author | pubmed-author:YamamuraYY | lld:pubmed |
| pubmed-article:6815094 | pubmed:author | pubmed-author:OkumuraHH | lld:pubmed |
| pubmed-article:6815094 | pubmed:author | pubmed-author:SaikiII | lld:pubmed |
| pubmed-article:6815094 | pubmed:author | pubmed-author:AzumaII | lld:pubmed |
| pubmed-article:6815094 | pubmed:author | pubmed-author:TanioYY | lld:pubmed |
| pubmed-article:6815094 | pubmed:author | pubmed-author:KamisangoKK | lld:pubmed |
| pubmed-article:6815094 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6815094 | pubmed:volume | 38 | lld:pubmed |
| pubmed-article:6815094 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6815094 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6815094 | pubmed:pagination | 58-65 | lld:pubmed |
| pubmed-article:6815094 | pubmed:dateRevised | 2010-9-13 | lld:pubmed |
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| pubmed-article:6815094 | pubmed:year | 1982 | lld:pubmed |
| pubmed-article:6815094 | pubmed:articleTitle | Adjuvant activity of purified peptidoglycan of Listeria monocytogenes in mice and guinea pigs. | lld:pubmed |
| pubmed-article:6815094 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6815094 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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