| pubmed-article:6795765 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6795765 | lifeskim:mentions | umls-concept:C0917798 | lld:lifeskim |
| pubmed-article:6795765 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:6795765 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:6795765 | lifeskim:mentions | umls-concept:C0060574 | lld:lifeskim |
| pubmed-article:6795765 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:6795765 | pubmed:dateCreated | 1982-1-9 | lld:pubmed |
| pubmed-article:6795765 | pubmed:abstractText | Fluosol-DA (Perfluorochemical Blood Substitutes) are small particle fluorocarbons suspended in an emulsion and have a high propensity for carrying oxygen and carbon dioxide. Fluosol-DA was investigated for the modification of acute focal cerebral ischemia and compared to mannitol. A total of 36 adult cats were divided into 3 groups and had transorbital microtourniquet ligation of the middle cerebral artery (MCA). Control animals were given intravenous isotonic saline. Animals in the experimental groups were treated with either intravenous Fluosol-DA or mannitol. All animals were nursed in an oxygen chamber and 4 cats from each group were sacrificed at 1, 3 and 6 hours after MCA occlusion. The results of macroscopic and histological examination of the brain suggested Fluosol-DA had a definite protective effect on acute focal cerebral ischemia which was in keeping with the observed neurological outcome. It is suggested that Fluosol-DA may support flow in the microcirculation and that the small particles of Fluosol-DA may be able to reach the area of ischemia via collaterals by decreasing blood viscosity, preventing narrowing of the arteriolar and capillary lumen and increasing the cerebral blood flow. | lld:pubmed |
| pubmed-article:6795765 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6795765 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6795765 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6795765 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6795765 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6795765 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6795765 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6795765 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6795765 | pubmed:issn | 0039-2499 | lld:pubmed |
| pubmed-article:6795765 | pubmed:author | pubmed-author:IshikawaRR | lld:pubmed |
| pubmed-article:6795765 | pubmed:author | pubmed-author:PeerlessS JSJ | lld:pubmed |
| pubmed-article:6795765 | pubmed:author | pubmed-author:HunterI GIG | lld:pubmed |
| pubmed-article:6795765 | pubmed:author | pubmed-author:PeerlessM JMJ | lld:pubmed |
| pubmed-article:6795765 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6795765 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:6795765 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6795765 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6795765 | pubmed:pagination | 558-63 | lld:pubmed |
| pubmed-article:6795765 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6795765 | pubmed:meshHeading | pubmed-meshheading:6795765-... | lld:pubmed |
| pubmed-article:6795765 | pubmed:meshHeading | pubmed-meshheading:6795765-... | lld:pubmed |
| pubmed-article:6795765 | pubmed:meshHeading | pubmed-meshheading:6795765-... | lld:pubmed |
| pubmed-article:6795765 | pubmed:meshHeading | pubmed-meshheading:6795765-... | lld:pubmed |
| pubmed-article:6795765 | pubmed:meshHeading | pubmed-meshheading:6795765-... | lld:pubmed |
| pubmed-article:6795765 | pubmed:meshHeading | pubmed-meshheading:6795765-... | lld:pubmed |
| pubmed-article:6795765 | pubmed:meshHeading | pubmed-meshheading:6795765-... | lld:pubmed |
| pubmed-article:6795765 | pubmed:articleTitle | Protective effect of Fluosol-DA in acute cerebral ischemia. | lld:pubmed |
| pubmed-article:6795765 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6795765 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:6795765 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6795765 | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6795765 | lld:pubmed |
