pubmed-article:6791782 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6791782 | lifeskim:mentions | umls-concept:C0025344 | lld:lifeskim |
pubmed-article:6791782 | lifeskim:mentions | umls-concept:C0222660 | lld:lifeskim |
pubmed-article:6791782 | lifeskim:mentions | umls-concept:C1280412 | lld:lifeskim |
pubmed-article:6791782 | lifeskim:mentions | umls-concept:C0158447 | lld:lifeskim |
pubmed-article:6791782 | lifeskim:mentions | umls-concept:C0444504 | lld:lifeskim |
pubmed-article:6791782 | lifeskim:mentions | umls-concept:C1641805 | lld:lifeskim |
pubmed-article:6791782 | lifeskim:mentions | umls-concept:C1522492 | lld:lifeskim |
pubmed-article:6791782 | lifeskim:mentions | umls-concept:C0677535 | lld:lifeskim |
pubmed-article:6791782 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:6791782 | pubmed:dateCreated | 1981-11-18 | lld:pubmed |
pubmed-article:6791782 | pubmed:abstractText | The mean wall thickness (MWT) and duration of formation periods (sigma f) of trabecular bone packets have been measured in iliac crest biopsies following double tetracycline labeling from 9 women having primary osteoporosis, with vertebral crush fractures and reduced trabecular bone volume (TBV), and 9 age- and sex-matched controls. The MWT of the osteoporotic biopsies was significantly less than that of the controls and was negatively correlated with age in the latter. There was also a positive correlation between MWT and TBV in the controls but not in the osteoporotics. Sigma f, in days, showed a tendency to decline with age in the control biopsies and was further decreased in the osteoporotic patients. These results suggest that a major contribution to the negative skeletal balance existing in both primary osteoporosis and physiological osteopenia is a decrease in bone formation, caused by a reduction in the life span of the osteoblastic population at the basic multicellular unit (BMU) level. | lld:pubmed |
pubmed-article:6791782 | pubmed:language | eng | lld:pubmed |
pubmed-article:6791782 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6791782 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6791782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6791782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6791782 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6791782 | pubmed:issn | 0171-967X | lld:pubmed |
pubmed-article:6791782 | pubmed:author | pubmed-author:DarbyA JAJ | lld:pubmed |
pubmed-article:6791782 | pubmed:author | pubmed-author:MeunierP JPJ | lld:pubmed |
pubmed-article:6791782 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6791782 | pubmed:volume | 33 | lld:pubmed |
pubmed-article:6791782 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6791782 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6791782 | pubmed:pagination | 199-204 | lld:pubmed |
pubmed-article:6791782 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:6791782 | pubmed:meshHeading | pubmed-meshheading:6791782-... | lld:pubmed |
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pubmed-article:6791782 | pubmed:meshHeading | pubmed-meshheading:6791782-... | lld:pubmed |
pubmed-article:6791782 | pubmed:year | 1981 | lld:pubmed |
pubmed-article:6791782 | pubmed:articleTitle | Mean wall thickness and formation periods of trabecular bone packets in idiopathic osteoporosis. | lld:pubmed |
pubmed-article:6791782 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6791782 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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