| pubmed-article:6789268 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6789268 | lifeskim:mentions | umls-concept:C0008976 | lld:lifeskim |
| pubmed-article:6789268 | lifeskim:mentions | umls-concept:C0008520 | lld:lifeskim |
| pubmed-article:6789268 | lifeskim:mentions | umls-concept:C0035298 | lld:lifeskim |
| pubmed-article:6789268 | lifeskim:mentions | umls-concept:C0018425 | lld:lifeskim |
| pubmed-article:6789268 | lifeskim:mentions | umls-concept:C0087162 | lld:lifeskim |
| pubmed-article:6789268 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:6789268 | pubmed:dateCreated | 1981-9-22 | lld:pubmed |
| pubmed-article:6789268 | pubmed:abstractText | Seven patients with gyrate atrophy and deficiency of ornithine-delta-aminotransferase were studied for in vivo pyridoxine responsiveness; three responded to oral vitamin B6 with over 50% reduction of serum ornithine levels and return to normal of serum lysine levels. Electrophysiologic studies were performed on two B6-responsive patients and one B6-nonresponder over various time periods with and without pyridoxine supplementation. Electroretinogram (ERG) amplitudes improved 100% in one patient when initially given high doses of vitamin B6. Electro-oculogram light-to-dark ratio also improved for this patient. Withdrawal followed by resumption of B6 supplementation was associated with mild worsening followed by improvement of ERG responses respectively in both patients. Long-term follow-up will be needed to assess whether pyridoxine treatment will slow or halt the progression of the disease. | lld:pubmed |
| pubmed-article:6789268 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6789268 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6789268 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6789268 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6789268 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6789268 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6789268 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6789268 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6789268 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:6789268 | pubmed:issn | 0161-6420 | lld:pubmed |
| pubmed-article:6789268 | pubmed:author | pubmed-author:KennawayN GNG | lld:pubmed |
| pubmed-article:6789268 | pubmed:author | pubmed-author:WeleberR GRG | lld:pubmed |
| pubmed-article:6789268 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6789268 | pubmed:volume | 88 | lld:pubmed |
| pubmed-article:6789268 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6789268 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6789268 | pubmed:pagination | 316-24 | lld:pubmed |
| pubmed-article:6789268 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:meshHeading | pubmed-meshheading:6789268-... | lld:pubmed |
| pubmed-article:6789268 | pubmed:year | 1981 | lld:pubmed |
| pubmed-article:6789268 | pubmed:articleTitle | Clinical trial of vitamin B6 for gyrate atrophy of the choroid and retina. | lld:pubmed |
| pubmed-article:6789268 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6789268 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:6789268 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6789268 | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6789268 | lld:pubmed |
