| pubmed-article:6694210 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6694210 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:6694210 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:6694210 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:6694210 | lifeskim:mentions | umls-concept:C2348519 | lld:lifeskim |
| pubmed-article:6694210 | lifeskim:mentions | umls-concept:C0058454 | lld:lifeskim |
| pubmed-article:6694210 | lifeskim:mentions | umls-concept:C0086149 | lld:lifeskim |
| pubmed-article:6694210 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:6694210 | pubmed:dateCreated | 1984-3-7 | lld:pubmed |
| pubmed-article:6694210 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:abstractText | The discoidin I genes of Dictyostelium form a small, co-ordinately regulated multigene family. We have sequenced and compared the upstream regions of the DiscI-alpha, -beta and -gamma genes. For the most part the upstream regions of the three genes are non-homologous. The upstream sequences of the beta and gamma genes are exceedingly A + T-rich, while those of the alpha gene are less so. All three genes have a relatively G + C-rich region 20 to 40 base-pairs in length, found approximately 200 base-pairs 5' to the messenger RNA start site. This G + C-rich region 5' to the beta and gamma genes is flanked by short inverted repeats. Within this region, there is an 11 base-pair exact homology between the alpha and gamma genes, and a less perfect homology between these genes and the beta gene. The homology is flanked at a short distance by interspersed G and T residues. The gamma gene is greater than 90% A + T for greater than 800 base-pairs upstream. Further upstream there is a G + C-rich region that is also found inverted approximately 3.5 X 10(3) base-pairs away. The gamma and beta genes are tandemly linked, and the entire approximately 500 base-pair intergene region between the 3' end of the gamma gene and the 5' end of the beta gene is A + T-rich (approximately 90%) with the exception of the homology region 5' to the gamma gene. We demonstrate also the presence of a discoidin I pseudogene fragment having only 139 base-pairs of discoidin homology with greater than 8% mismatch. It is flanked upstream by five 39 base-pair G + C-rich repeats, and downstream by sequences that are extremely A + T-rich. We discuss the possible significance of the conserved G + C-rich structures on discoidin I gene expression. | lld:pubmed |
| pubmed-article:6694210 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6694210 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6694210 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6694210 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6694210 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:6694210 | pubmed:issn | 0022-2836 | lld:pubmed |
| pubmed-article:6694210 | pubmed:author | pubmed-author:FirtelR ARA | lld:pubmed |
| pubmed-article:6694210 | pubmed:author | pubmed-author:PooleS JSJ | lld:pubmed |
| pubmed-article:6694210 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6694210 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:6694210 | pubmed:volume | 172 | lld:pubmed |
| pubmed-article:6694210 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6694210 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6694210 | pubmed:pagination | 203-20 | lld:pubmed |
| pubmed-article:6694210 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6694210 | pubmed:meshHeading | pubmed-meshheading:6694210-... | lld:pubmed |
| pubmed-article:6694210 | pubmed:meshHeading | pubmed-meshheading:6694210-... | lld:pubmed |
| pubmed-article:6694210 | pubmed:meshHeading | pubmed-meshheading:6694210-... | lld:pubmed |
| pubmed-article:6694210 | pubmed:meshHeading | pubmed-meshheading:6694210-... | lld:pubmed |
| pubmed-article:6694210 | pubmed:meshHeading | pubmed-meshheading:6694210-... | lld:pubmed |
| pubmed-article:6694210 | pubmed:meshHeading | pubmed-meshheading:6694210-... | lld:pubmed |
| pubmed-article:6694210 | pubmed:meshHeading | pubmed-meshheading:6694210-... | lld:pubmed |
| pubmed-article:6694210 | pubmed:meshHeading | pubmed-meshheading:6694210-... | lld:pubmed |
| pubmed-article:6694210 | pubmed:meshHeading | pubmed-meshheading:6694210-... | lld:pubmed |
| pubmed-article:6694210 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6694210 | pubmed:articleTitle | Conserved structural features are found upstream from the three co-ordinately regulated discoidin I genes of Dictyostelium discoideum. | lld:pubmed |
| pubmed-article:6694210 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6694210 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6694210 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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