| pubmed-article:6681687 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C0001554 | lld:lifeskim |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C0443315 | lld:lifeskim |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C0037663 | lld:lifeskim |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C0169964 | lld:lifeskim |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C0205307 | lld:lifeskim |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C0011155 | lld:lifeskim |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C0237662 | lld:lifeskim |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C1979963 | lld:lifeskim |
| pubmed-article:6681687 | lifeskim:mentions | umls-concept:C2003903 | lld:lifeskim |
| pubmed-article:6681687 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6681687 | pubmed:dateCreated | 1983-3-24 | lld:pubmed |
| pubmed-article:6681687 | pubmed:abstractText | The time course of plasma growth hormone (hGH) levels following sc and im injection of hGH was studied in 12 children with growth hormone deficiency who had received long-term treatment with im injections of highly purified hGH. Also the spontaneous diurnal GH levels in 8 normal children of comparable age were recorded. Blood samples were obtained during 24 h after im and sc injections of 4 IU/m2 hGH and analysed for immunoreactive hGH. While a median peak value of 160 ng/ml (range 135 to 475 ng/ml) was obtained 2 h after im injection, sc injection resulted in a more sustained elevation reaching 41 ng/ml (range 32 to 51 ng/ml) at 6 h subsiding slowly with a median concentration of 15 ng/ml (range 5-24 ng/ml) persisting after 14 h. Gel chromatography demonstrated that the hGH immunoreactivity of blood samples obtained as late as 14 h after sc injection had unaltered molecular size. Seven of the patients were further studied after sc injection of 2 IU/m2 at 20.00 h instead of in the morning. A plasma profile was attained during the night which roughly approximated the average nocturnal plasma pattern of the normal children. | lld:pubmed |
| pubmed-article:6681687 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6681687 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6681687 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6681687 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6681687 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6681687 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:6681687 | pubmed:issn | 0001-5598 | lld:pubmed |
| pubmed-article:6681687 | pubmed:author | pubmed-author:OrskovHH | lld:pubmed |
| pubmed-article:6681687 | pubmed:author | pubmed-author:BinderCC | lld:pubmed |
| pubmed-article:6681687 | pubmed:author | pubmed-author:ChristiansenJ... | lld:pubmed |
| pubmed-article:6681687 | pubmed:author | pubmed-author:KastrupK WKW | lld:pubmed |
| pubmed-article:6681687 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6681687 | pubmed:volume | 102 | lld:pubmed |
| pubmed-article:6681687 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6681687 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6681687 | pubmed:pagination | 6-10 | lld:pubmed |
| pubmed-article:6681687 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6681687 | pubmed:meshHeading | pubmed-meshheading:6681687-... | lld:pubmed |
| pubmed-article:6681687 | pubmed:meshHeading | pubmed-meshheading:6681687-... | lld:pubmed |
| pubmed-article:6681687 | pubmed:meshHeading | pubmed-meshheading:6681687-... | lld:pubmed |
| pubmed-article:6681687 | pubmed:meshHeading | pubmed-meshheading:6681687-... | lld:pubmed |
| pubmed-article:6681687 | pubmed:meshHeading | pubmed-meshheading:6681687-... | lld:pubmed |
| pubmed-article:6681687 | pubmed:meshHeading | pubmed-meshheading:6681687-... | lld:pubmed |
| pubmed-article:6681687 | pubmed:meshHeading | pubmed-meshheading:6681687-... | lld:pubmed |
| pubmed-article:6681687 | pubmed:meshHeading | pubmed-meshheading:6681687-... | lld:pubmed |
| pubmed-article:6681687 | pubmed:meshHeading | pubmed-meshheading:6681687-... | lld:pubmed |
| pubmed-article:6681687 | pubmed:meshHeading | pubmed-meshheading:6681687-... | lld:pubmed |
| pubmed-article:6681687 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6681687 | pubmed:articleTitle | Imitation of normal plasma growth hormone profile by subcutaneous administration of human growth hormone to growth hormone deficient children. | lld:pubmed |
| pubmed-article:6681687 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6681687 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6681687 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6681687 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6681687 | lld:pubmed |
