| pubmed-article:6669615 | pubmed:abstractText | By the example of the model drug phenobarbital, the authors report of the possibilities of influencing the liberation of drugs from acrylate-based bead polymers. The drug-containing bead polymers produced were studied in vitro (half-change method, beaker device according to Moldenhauer, artificial digestive juices according to Münzel, without addition of enzymes). The composition of a unit-dose preparation, composed of several batches prepared under different conditions, is dealt with. The release values obtained largely meet the requirements made on depot preparations. | lld:pubmed |
