| pubmed-article:6668451 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6668451 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:6668451 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:6668451 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:6668451 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:6668451 | lifeskim:mentions | umls-concept:C0023820 | lld:lifeskim |
| pubmed-article:6668451 | lifeskim:mentions | umls-concept:C0052181 | lld:lifeskim |
| pubmed-article:6668451 | lifeskim:mentions | umls-concept:C1416804 | lld:lifeskim |
| pubmed-article:6668451 | lifeskim:mentions | umls-concept:C1264633 | lld:lifeskim |
| pubmed-article:6668451 | lifeskim:mentions | umls-concept:C1704711 | lld:lifeskim |
| pubmed-article:6668451 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:6668451 | pubmed:dateCreated | 1984-4-11 | lld:pubmed |
| pubmed-article:6668451 | pubmed:abstractText | Plasma samples were incubated under various conditions to study the effect of in vitro incubation on apolipoprotein A-IV distribution between the lipoprotein and lipoprotein-free fractions. When plasma was fractionated immediately after bleeding, apolipoprotein A-IV was present in equal concentrations in the lipoprotein and lipoprotein-free fractions. After a 4-hr, 37 degrees C incubation, greater than 90% of total plasma apolipoprotein A-IV was present in the lipoprotein fraction and the percentage of plasma cholesterol present as cholesteryl ester increased from 58% to 74%. When plasma was incubated for 4 hr at 37 degrees C in the presence of 1.5 mM 5,5-dithiobis(2-nitrobenzoic acid) (DTNB), greater than 90% of total plasma apoA-IV was present in the lipoprotein-free fraction, whereas plasma cholesteryl ester concentration did not change. Incubating heat-inactivated plasma for 4 hr also resulted in the redistribution of apolipoprotein A-IV from the lipoprotein fraction to the lipoprotein-free fraction, concurrent with no change in cholesterol esterification. When heat-inactivated plasma was incubated in the presence of a purified lecithin:cholesterol acyltransferase preparation, cholesterol esterification was restored and apolipoprotein A-IV was redistributed from the lipoprotein-free fraction to the lipoprotein fraction in such a manner that greater than 90% was present in the lipoprotein fraction. No changes in apolipoprotein A-I and apolipoprotein E distributions were found under any of the above conditions. Thus, the in vitro plasma incubations show that apolipoprotein A-IV can move bidirectionally between lipoprotein and lipoprotein-free fractions; the direction of this movement depends on the condition of the incubation.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
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| pubmed-article:6668451 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6668451 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6668451 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:6668451 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6668451 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:6668451 | pubmed:issn | 0022-2275 | lld:pubmed |
| pubmed-article:6668451 | pubmed:author | pubmed-author:RoheimP SPS | lld:pubmed |
| pubmed-article:6668451 | pubmed:author | pubmed-author:LackoA GAG | lld:pubmed |
| pubmed-article:6668451 | pubmed:author | pubmed-author:DeLamatreJ... | lld:pubmed |
| pubmed-article:6668451 | pubmed:author | pubmed-author:HoffmeierC... | lld:pubmed |
| pubmed-article:6668451 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6668451 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:6668451 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6668451 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6668451 | pubmed:pagination | 1578-85 | lld:pubmed |
| pubmed-article:6668451 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:6668451 | pubmed:meshHeading | pubmed-meshheading:6668451-... | lld:pubmed |
| pubmed-article:6668451 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6668451 | pubmed:articleTitle | Distribution of apolipoprotein A-IV between the lipoprotein and the lipoprotein-free fractions of rat plasma: possible role of lecithin:cholesterol acyltransferase. | lld:pubmed |
| pubmed-article:6668451 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6668451 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6668451 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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