| pubmed-article:6604585 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6604585 | lifeskim:mentions | umls-concept:C0024109 | lld:lifeskim |
| pubmed-article:6604585 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:6604585 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:6604585 | lifeskim:mentions | umls-concept:C0020522 | lld:lifeskim |
| pubmed-article:6604585 | lifeskim:mentions | umls-concept:C0030956 | lld:lifeskim |
| pubmed-article:6604585 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6604585 | pubmed:dateCreated | 1983-11-23 | lld:pubmed |
| pubmed-article:6604585 | pubmed:abstractText | The development of immunity to homologous connective tissue antigens was studied with respect to aging in the tight-skin (Tsk) mouse mutant. A delayed-type hypersensitivity (DTH) response to elastase-solubilized lung peptides in Tsk/+ mice, which became evident at 10 weeks of age and increased in intensity until 22 weeks, was observed. Tsk mice did not demonstrate significant DTH responses when challenged with type I or IV collagen, and normal (+/+) littermates of all ages did not respond to any of the antigens under study. DTH responses could be adoptively transferred to normal +/+ and C57BL/6 mice with spleen cells from 30-week-old Tsk/+ mice; treatment with anti-Thy 1.2 antibodies plus complement significantly reduced the ability of these Tsk/+ cells to transfer DTH reactivity. No antibody activity to the antigens under study could be detected in the sera of Tsk/+ or +/+ mice at any age. These results are discussed with regard to the pathological manifestations observed in the Tsk/+ mutant mouse. | lld:pubmed |
| pubmed-article:6604585 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6604585 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6604585 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6604585 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6604585 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6604585 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6604585 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6604585 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:6604585 | pubmed:issn | 0008-8749 | lld:pubmed |
| pubmed-article:6604585 | pubmed:author | pubmed-author:LeRoyE CEC | lld:pubmed |
| pubmed-article:6604585 | pubmed:author | pubmed-author:DeLustroF AFA | lld:pubmed |
| pubmed-article:6604585 | pubmed:author | pubmed-author:MackelA MAM | lld:pubmed |
| pubmed-article:6604585 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6604585 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:6604585 | pubmed:volume | 81 | lld:pubmed |
| pubmed-article:6604585 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6604585 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6604585 | pubmed:pagination | 175-9 | lld:pubmed |
| pubmed-article:6604585 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:6604585 | pubmed:meshHeading | pubmed-meshheading:6604585-... | lld:pubmed |
| pubmed-article:6604585 | pubmed:meshHeading | pubmed-meshheading:6604585-... | lld:pubmed |
| pubmed-article:6604585 | pubmed:meshHeading | pubmed-meshheading:6604585-... | lld:pubmed |
| pubmed-article:6604585 | pubmed:meshHeading | pubmed-meshheading:6604585-... | lld:pubmed |
| pubmed-article:6604585 | pubmed:meshHeading | pubmed-meshheading:6604585-... | lld:pubmed |
| pubmed-article:6604585 | pubmed:meshHeading | pubmed-meshheading:6604585-... | lld:pubmed |
| pubmed-article:6604585 | pubmed:meshHeading | pubmed-meshheading:6604585-... | lld:pubmed |
| pubmed-article:6604585 | pubmed:meshHeading | pubmed-meshheading:6604585-... | lld:pubmed |
| pubmed-article:6604585 | pubmed:meshHeading | pubmed-meshheading:6604585-... | lld:pubmed |
| pubmed-article:6604585 | pubmed:meshHeading | pubmed-meshheading:6604585-... | lld:pubmed |
| pubmed-article:6604585 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6604585 | pubmed:articleTitle | Delayed-type hypersensitivity to elastase-soluble lung peptides in the tight-skin (Tsk) mouse. | lld:pubmed |
| pubmed-article:6604585 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6604585 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| entrez-gene:14118 | entrezgene:pubmed | pubmed-article:6604585 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6604585 | lld:pubmed |
