| pubmed-article:6600222 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6600222 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:6600222 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:6600222 | lifeskim:mentions | umls-concept:C0241764 | lld:lifeskim |
| pubmed-article:6600222 | lifeskim:mentions | umls-concept:C0205161 | lld:lifeskim |
| pubmed-article:6600222 | lifeskim:mentions | umls-concept:C0535968 | lld:lifeskim |
| pubmed-article:6600222 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:6600222 | pubmed:dateCreated | 1983-2-25 | lld:pubmed |
| pubmed-article:6600222 | pubmed:abstractText | The effect of extracellular phosphate on the control of 25-hydroxyvitamin D3 24-hydroxylase was studied in normal mice and littermates with X-linked hypophosphatemic rickets (Hyp). 24-Hydroxylase activity and plasma concentrations of 24,25-dihydroxyvitamin D3 were significantly higher in Hyp mice than in normal mice when both groups were fed a normal diet containing 1.22% calcium (Ca) and 0.8% phosphorus (Pi). The differential in 24-hydroxylase activity was exaggerated when serum phosphate was reduced in normal mice by means of a low Pi diet or increased in Hyp mice by means of a high Pi diet. Differences in 24-hydroxylase activity between the two groups of mice were also demonstrated in the presence of varying Pi concentrations in vitro. Thus, in both Hyp and normal mice, 24-hydroxylase activity is influenced in a qualitatively similar manner by serum Pi. Plasma concentrations of 1,25-dihydroxyvitamin D3 were the same in normal and Hyp mice. The data are consistent with the hypothesis that control the renal metabolism of 25-hydroxyvitamin D3 in Hyp mice is reset such tht 24-hydroxylase activity is inappropriate high for the prevailing serum phosphate over a wide range of concentrations. | lld:pubmed |
| pubmed-article:6600222 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6600222 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6600222 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6600222 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6600222 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:6600222 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6600222 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:6600222 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6600222 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6600222 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6600222 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6600222 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6600222 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6600222 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6600222 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:6600222 | pubmed:issn | 0013-7227 | lld:pubmed |
| pubmed-article:6600222 | pubmed:author | pubmed-author:SeinoYY | lld:pubmed |
| pubmed-article:6600222 | pubmed:author | pubmed-author:CunninghamJJ | lld:pubmed |
| pubmed-article:6600222 | pubmed:author | pubmed-author:ChengP YPY | lld:pubmed |
| pubmed-article:6600222 | pubmed:author | pubmed-author:GomezAA | lld:pubmed |
| pubmed-article:6600222 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6600222 | pubmed:volume | 112 | lld:pubmed |
| pubmed-article:6600222 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6600222 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6600222 | pubmed:pagination | 633-8 | lld:pubmed |
| pubmed-article:6600222 | pubmed:dateRevised | 2008-8-16 | lld:pubmed |
| pubmed-article:6600222 | pubmed:meshHeading | pubmed-meshheading:6600222-... | lld:pubmed |
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| pubmed-article:6600222 | pubmed:meshHeading | pubmed-meshheading:6600222-... | lld:pubmed |
| pubmed-article:6600222 | pubmed:meshHeading | pubmed-meshheading:6600222-... | lld:pubmed |
| pubmed-article:6600222 | pubmed:meshHeading | pubmed-meshheading:6600222-... | lld:pubmed |
| pubmed-article:6600222 | pubmed:meshHeading | pubmed-meshheading:6600222-... | lld:pubmed |
| pubmed-article:6600222 | pubmed:meshHeading | pubmed-meshheading:6600222-... | lld:pubmed |
| pubmed-article:6600222 | pubmed:meshHeading | pubmed-meshheading:6600222-... | lld:pubmed |
| pubmed-article:6600222 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6600222 | pubmed:articleTitle | Abnormal 24-hydroxylation of 25-hydroxyvitamin D in the X-linked hypophosphatemic mouse. | lld:pubmed |
| pubmed-article:6600222 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6600222 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6600222 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6600222 | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6600222 | lld:pubmed |
