| pubmed-article:6524900 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6524900 | lifeskim:mentions | umls-concept:C0004034 | lld:lifeskim |
| pubmed-article:6524900 | lifeskim:mentions | umls-concept:C0039644 | lld:lifeskim |
| pubmed-article:6524900 | lifeskim:mentions | umls-concept:C0002679 | lld:lifeskim |
| pubmed-article:6524900 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:6524900 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:6524900 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:6524900 | lifeskim:mentions | umls-concept:C2349975 | lld:lifeskim |
| pubmed-article:6524900 | lifeskim:mentions | umls-concept:C1627358 | lld:lifeskim |
| pubmed-article:6524900 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:6524900 | pubmed:dateCreated | 1985-3-18 | lld:pubmed |
| pubmed-article:6524900 | pubmed:abstractText | Strains of Aspergillus fumigatus, Aspergillus flavus, and Aspergillus niger were tested for in vitro susceptibility to amphotericin B alone and in combination with fixed concentrations of tetracycline, doxycycline, or minocycline, using buffered minimal essential medium in microtiter plates. Enhanced inhibitory activity was seen, especially with combinations of amphotericin B and minocycline. Synergistic activity between amphotericin B and minocycline was observed in each of five isolates of each species when tested in a checkerboard dilution scheme. Time-kill curves demonstrated killing an A. fumigatus isolated at concentrations of amphotericin B that were four- or eightfold lower in the presence of 5 or 15 micrograms of minocycline per ml than with amphotericin B alone. Of the tetracycline analogs tested, minocycline has the greatest activity against A. fumigatus, A. flavus, and A. niger conidia when potentiated by amphotericin B. | lld:pubmed |
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| pubmed-article:6524900 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6524900 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6524900 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6524900 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:6524900 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6524900 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:6524900 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:6524900 | pubmed:author | pubmed-author:PetersonL RLR | lld:pubmed |
| pubmed-article:6524900 | pubmed:author | pubmed-author:GerdingD NDN | lld:pubmed |
| pubmed-article:6524900 | pubmed:author | pubmed-author:HarrisCC | lld:pubmed |
| pubmed-article:6524900 | pubmed:author | pubmed-author:HughesC ECE | lld:pubmed |
| pubmed-article:6524900 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6524900 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:6524900 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6524900 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6524900 | pubmed:pagination | 837-40 | lld:pubmed |
| pubmed-article:6524900 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:6524900 | pubmed:meshHeading | pubmed-meshheading:6524900-... | lld:pubmed |
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| pubmed-article:6524900 | pubmed:meshHeading | pubmed-meshheading:6524900-... | lld:pubmed |
| pubmed-article:6524900 | pubmed:meshHeading | pubmed-meshheading:6524900-... | lld:pubmed |
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| pubmed-article:6524900 | pubmed:meshHeading | pubmed-meshheading:6524900-... | lld:pubmed |
| pubmed-article:6524900 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6524900 | pubmed:articleTitle | Enhancement of the in vitro activity of amphotericin B against Aspergillus spp. by tetracycline analogs. | lld:pubmed |
| pubmed-article:6524900 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6524900 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:6524900 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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