| pubmed-article:6491813 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6491813 | lifeskim:mentions | umls-concept:C0034493 | lld:lifeskim |
| pubmed-article:6491813 | lifeskim:mentions | umls-concept:C0007303 | lld:lifeskim |
| pubmed-article:6491813 | lifeskim:mentions | umls-concept:C0022745 | lld:lifeskim |
| pubmed-article:6491813 | lifeskim:mentions | umls-concept:C0033692 | lld:lifeskim |
| pubmed-article:6491813 | lifeskim:mentions | umls-concept:C0039099 | lld:lifeskim |
| pubmed-article:6491813 | lifeskim:mentions | umls-concept:C1524003 | lld:lifeskim |
| pubmed-article:6491813 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:6491813 | pubmed:dateCreated | 1984-12-13 | lld:pubmed |
| pubmed-article:6491813 | pubmed:abstractText | Proteoglycans (PGs) isolated from articular cartilage (AC) of mature rabbits subjected to two or more consecutive intraarticular (IA) injections of sterile saline 24 h apart showed an aggregation defect in the presence of excess hyaluronic acid (HA). Although the PG contents of experimental and control cartilages were indistinguishable, a higher proportion of PGs were extractable from the 3 X IA tissues, as assessed by uronic acid analysis. Proteoglycans from experimental and control cartilages when examined by Sepharose CL-2B chromatography showed two subunit populations, the smaller (KAV = 0.70) containing more ketatan sulphate than the larger (KAV = 0.31). Cultures of AC from IA joints released more 35SO4-labelled PGs into the media over 72 h than control tissues and consisted mainly of PG degradation products although 20% could aggregate in the presence of HA. Examination of PG aggregation 2 weeks after 2 X IA or 3 X IA injections showed that the defect initiated was still present; however, cartilage of immature rabbits was not affected by the 2 X IA procedure. | lld:pubmed |
| pubmed-article:6491813 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6491813 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6491813 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6491813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6491813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6491813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6491813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6491813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6491813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6491813 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6491813 | pubmed:issn | 0736-0266 | lld:pubmed |
| pubmed-article:6491813 | pubmed:author | pubmed-author:GhoseSS | lld:pubmed |
| pubmed-article:6491813 | pubmed:author | pubmed-author:GROFFH DHD | lld:pubmed |
| pubmed-article:6491813 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6491813 | pubmed:volume | 2 | lld:pubmed |
| pubmed-article:6491813 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6491813 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6491813 | pubmed:pagination | 207-20 | lld:pubmed |
| pubmed-article:6491813 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:meshHeading | pubmed-meshheading:6491813-... | lld:pubmed |
| pubmed-article:6491813 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6491813 | pubmed:articleTitle | Microinjury to the synovial membrane may cause disaggregation of proteoglycans in rabbit knee joint articular cartilage. | lld:pubmed |
| pubmed-article:6491813 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6491813 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
