pubmed-article:6458977 | pubmed:abstractText | Among cutaneous propionibacteria, synthesis of neuraminidase is highest in strains of the species P, acnes. In the present study, neuraminidase activity was discovered in 90.0% of P. acnes strains isolated from acne lesions compared with 72.7% of strains from normal human skin. Neuraminidase-positive strains from acne lesions, moreover, produced statistically significant higher amounts of the enzyme (X = 727 microunits/ml bacterial suspension) than isolates from normal skin (X - 392 microunits/ml). Whereas the moderate production of neuraminidase by strains from patients with seborrheic eczema is probably of no causative importance, the enzyme has to be discussed a potential etiologic factor in acne vulgaris. | lld:pubmed |