| pubmed-article:6450236 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C0032659 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C0003962 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C0019630 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C0441471 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C0205374 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:6450236 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:6450236 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6450236 | pubmed:dateCreated | 1981-3-27 | lld:pubmed |
| pubmed-article:6450236 | pubmed:abstractText | We have evaluated the biosynthesis and surface expression of I-A antigens by peritoneal macrophages and found that both events terminated during the 1st day in culture, in contrast to the undiminished synthesis and expression of H-2K antigens. This pattern was observed regardless of the means by which the macrophages were elicited, but was subject to modulation for a limited period of time in vitro: phagocytic stimuli were able to augment both I-A synthesis and expression. The loss of I-A and the re-expression after phagocytosis were both reflected in the stimulatory capacity of these macrophages in the mixed leukocyte reaction. Moreover, we found that I-A-bearing macrophages were lost from the exudate in vivo after irradiation. Our data suggest that, as in vitro, this phenomenon is due to the transition of individual macrophages from I-A-positive to I-A-negative, and that constant renewal is required to maintain the I-A-bearing subset in vivo. | lld:pubmed |
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| pubmed-article:6450236 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6450236 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6450236 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:6450236 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6450236 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:6450236 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:6450236 | pubmed:author | pubmed-author:UnanueE RER | lld:pubmed |
| pubmed-article:6450236 | pubmed:author | pubmed-author:BellerD IDI | lld:pubmed |
| pubmed-article:6450236 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6450236 | pubmed:volume | 126 | lld:pubmed |
| pubmed-article:6450236 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6450236 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6450236 | pubmed:pagination | 263-9 | lld:pubmed |
| pubmed-article:6450236 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:6450236 | pubmed:year | 1981 | lld:pubmed |
| pubmed-article:6450236 | pubmed:articleTitle | Regulation of macrophage populations. II. Synthesis and expression of Ia antigens by peritoneal exudate macrophages is a transient event. | lld:pubmed |
| pubmed-article:6450236 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6450236 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6450236 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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