| pubmed-article:6402059 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6402059 | lifeskim:mentions | umls-concept:C0011854 | lld:lifeskim |
| pubmed-article:6402059 | lifeskim:mentions | umls-concept:C0041432 | lld:lifeskim |
| pubmed-article:6402059 | lifeskim:mentions | umls-concept:C0019764 | lld:lifeskim |
| pubmed-article:6402059 | lifeskim:mentions | umls-concept:C1705241 | lld:lifeskim |
| pubmed-article:6402059 | lifeskim:mentions | umls-concept:C0441704 | lld:lifeskim |
| pubmed-article:6402059 | lifeskim:mentions | umls-concept:C1709450 | lld:lifeskim |
| pubmed-article:6402059 | lifeskim:mentions | umls-concept:C1705242 | lld:lifeskim |
| pubmed-article:6402059 | pubmed:issue | 6361 | lld:pubmed |
| pubmed-article:6402059 | pubmed:dateCreated | 1983-4-7 | lld:pubmed |
| pubmed-article:6402059 | pubmed:abstractText | A total of 106 pairs of identical twins, of whom 56 were concordant and 50 discordant for insulin-dependent diabetes, were typed for HLA-DR. In both the concordant and discordant groups there was a high prevalence of the antigens DR3 and DR4, a low prevalence of DR5 and DR7, and a virtual absence of DR2. The heterozygous phenotype DR3,DR4 was more prevalent in concordant than discordant pairs. This was therefore the first demonstration of a genetic difference between concordant and discordant identical twin pairs. These findings suggest that possession of both DR3 and DR4 antigens confers a greater genetic predisposition to insulin-dependent diabetes than does the possession of either antigen alone. | lld:pubmed |
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| pubmed-article:6402059 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:6402059 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:6402059 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6402059 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:6402059 | pubmed:issn | 0267-0623 | lld:pubmed |
| pubmed-article:6402059 | pubmed:author | pubmed-author:CudworthA GAG | lld:pubmed |
| pubmed-article:6402059 | pubmed:author | pubmed-author:WolfEE | lld:pubmed |
| pubmed-article:6402059 | pubmed:author | pubmed-author:PykeD ADA | lld:pubmed |
| pubmed-article:6402059 | pubmed:author | pubmed-author:JohnstonCC | lld:pubmed |
| pubmed-article:6402059 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6402059 | pubmed:day | 22 | lld:pubmed |
| pubmed-article:6402059 | pubmed:volume | 286 | lld:pubmed |
| pubmed-article:6402059 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6402059 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6402059 | pubmed:pagination | 253-5 | lld:pubmed |
| pubmed-article:6402059 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6402059 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6402059 | pubmed:articleTitle | HLA-DR typing in identical twins with insulin-dependent diabetes: difference between concordant and discordant pairs. | lld:pubmed |
| pubmed-article:6402059 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6402059 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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