| pubmed-article:6400825 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6400825 | lifeskim:mentions | umls-concept:C1705165 | lld:lifeskim |
| pubmed-article:6400825 | lifeskim:mentions | umls-concept:C0026377 | lld:lifeskim |
| pubmed-article:6400825 | lifeskim:mentions | umls-concept:C0037812 | lld:lifeskim |
| pubmed-article:6400825 | lifeskim:mentions | umls-concept:C2700061 | lld:lifeskim |
| pubmed-article:6400825 | lifeskim:mentions | umls-concept:C0441712 | lld:lifeskim |
| pubmed-article:6400825 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:6400825 | pubmed:dateCreated | 1990-3-14 | lld:pubmed |
| pubmed-article:6400825 | pubmed:abstractText | The helical structures of d(C-G-m5C-G-C-G) were studied in aqueous solution at various salt concentrations and temperatures by CD and 1H-NMR spectroscopy. At room temperature only the B form is observed in 0.1 M NaCl whereas the B and Z forms are simultaneously present in 1.8 M NaCl. At high salt concentration (4 M NaCl) the Z form is largely predominant (greater than 95%). The Z form proton resonances were assigned by using the polarisation transfer method (between B and Z at 1.8 M NaCl) and by proton-proton decoupling (at high salt concentration). The Z-B-Coil transitions were studied as a function of temperature with the 1.8 M NaCl solution. At high temperature (95 degrees C) only the coil form (S) is present. Below 55 degrees C the coil proportion is negligible, and the B-Z exchange is slow. The disappearance of the coil gives rise at first to the B form and on lowering the temperature the Z proportion increases to the detriment of the B form. Proton linewidth, relaxation and polarisation transfer studies confirm the conclusion in the previous report on d(m5C-G-C-G-m5C-G) (Tran-Dinh et al Biochemistry 1984 in the press) that Z exchanges only with B whereas the latter also exchanges with S,Z in equilibrium B in equilibrium S. The present data show that even at high salt concentration where only the Z form of d(C-G-m5C-G-C-G) is observed the Z-S transition also passes through the B form as an intermediate stage. The B-Z transition takes place when the Watson-Crick hydrogen bonds are firmly maintained and is greatly favoured when there are three hydrogen bonds between the base-pairs. | lld:pubmed |
| pubmed-article:6400825 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6400825 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6400825 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6400825 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6400825 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6400825 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6400825 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6400825 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:6400825 | pubmed:issn | 0739-1102 | lld:pubmed |
| pubmed-article:6400825 | pubmed:author | pubmed-author:Tran-DinhSS | lld:pubmed |
| pubmed-article:6400825 | pubmed:author | pubmed-author:NeumannJ MJM | lld:pubmed |
| pubmed-article:6400825 | pubmed:author | pubmed-author:TabouryJJ | lld:pubmed |
| pubmed-article:6400825 | pubmed:author | pubmed-author:IgolenJJ | lld:pubmed |
| pubmed-article:6400825 | pubmed:author | pubmed-author:Huynh-DinhTT | lld:pubmed |
| pubmed-article:6400825 | pubmed:author | pubmed-author:Langlois... | lld:pubmed |
| pubmed-article:6400825 | pubmed:author | pubmed-author:CavaillesJ... | lld:pubmed |
| pubmed-article:6400825 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6400825 | pubmed:volume | 1 | lld:pubmed |
| pubmed-article:6400825 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6400825 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6400825 | pubmed:pagination | 1347-71 | lld:pubmed |
| pubmed-article:6400825 | pubmed:dateRevised | 2000-12-18 | lld:pubmed |
| pubmed-article:6400825 | pubmed:meshHeading | pubmed-meshheading:6400825-... | lld:pubmed |
| pubmed-article:6400825 | pubmed:meshHeading | pubmed-meshheading:6400825-... | lld:pubmed |
| pubmed-article:6400825 | pubmed:meshHeading | pubmed-meshheading:6400825-... | lld:pubmed |
| pubmed-article:6400825 | pubmed:meshHeading | pubmed-meshheading:6400825-... | lld:pubmed |
| pubmed-article:6400825 | pubmed:meshHeading | pubmed-meshheading:6400825-... | lld:pubmed |
| pubmed-article:6400825 | pubmed:meshHeading | pubmed-meshheading:6400825-... | lld:pubmed |
| pubmed-article:6400825 | pubmed:meshHeading | pubmed-meshheading:6400825-... | lld:pubmed |
| pubmed-article:6400825 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6400825 | pubmed:articleTitle | B,Z conformations and mechanism of the Z-B-coil transitions of the self-complementary deoxy-hexanucleotide d(C-G-m5C-G-C-G) by 1H-NMR and CD spectroscopy. | lld:pubmed |
| pubmed-article:6400825 | pubmed:affiliation | Service de Biophysique Department de Biologie, Centre d'Etudes Nucléaires de Saclay, Gif-sur-Yvette, France. | lld:pubmed |
| pubmed-article:6400825 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6400825 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6400825 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6400825 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6400825 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6400825 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6400825 | lld:pubmed |
