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| pubmed-article:6373610 | lifeskim:mentions | umls-concept:C0238200 | lld:lifeskim |
| pubmed-article:6373610 | lifeskim:mentions | umls-concept:C0021270 | lld:lifeskim |
| pubmed-article:6373610 | lifeskim:mentions | umls-concept:C0007635 | lld:lifeskim |
| pubmed-article:6373610 | lifeskim:mentions | umls-concept:C0014335 | lld:lifeskim |
| pubmed-article:6373610 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
| pubmed-article:6373610 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:6373610 | lifeskim:mentions | umls-concept:C1510802 | lld:lifeskim |
| pubmed-article:6373610 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:6373610 | lifeskim:mentions | umls-concept:C0205321 | lld:lifeskim |
| pubmed-article:6373610 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:6373610 | pubmed:dateCreated | 1984-7-17 | lld:pubmed |
| pubmed-article:6373610 | pubmed:abstractText | The adherence of invasive Escherichia coli strains 444-3 and 469-3 to human erythrocytes and to cultured HeLa and HEp-2 cells has been examined by electron microscopy. Bacteria elaborating type 1 fimbriae, glycocalyces , and nonfimbrial mannose-resistant hemagglutinins specific for human erythrocytes were identified in cultures of both strains, and each of these different bacterial surface components appeared to be involved in attachment of 444-3 and 469-3 to cultured epithelial cells or human erythrocytes (or to both). Both strains, which were isolated from infants with dysentery-like illness, penetrated cultured epithelial cells and existed within membrane-bounded intracellular vesicles. Mutants of 444-3 and 469-3 selected for deficiency in mannose-resistant hemagglutination did not adhere to or penetrate cultured cells. These ultrastructural studies demonstrate the complexity of the bacterial surface and show that E. coli strains 444-3 and 469-3 can elaborate several different adhesions , each of which could function to promote attachment to host intestinal epithelial cells. Mucosal invasion may also be an important virulence property of these strains. | lld:pubmed |
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| pubmed-article:6373610 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6373610 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6373610 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6373610 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6373610 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:6373610 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:6373610 | pubmed:author | pubmed-author:McNeishA SAS | lld:pubmed |
| pubmed-article:6373610 | pubmed:author | pubmed-author:KnuttonSS | lld:pubmed |
| pubmed-article:6373610 | pubmed:author | pubmed-author:WilliamsP HPH | lld:pubmed |
| pubmed-article:6373610 | pubmed:author | pubmed-author:CandyD CDC | lld:pubmed |
| pubmed-article:6373610 | pubmed:author | pubmed-author:LloydD RDR | lld:pubmed |
| pubmed-article:6373610 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6373610 | pubmed:volume | 44 | lld:pubmed |
| pubmed-article:6373610 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6373610 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6373610 | pubmed:pagination | 599-608 | lld:pubmed |
| pubmed-article:6373610 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6373610 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6373610 | pubmed:articleTitle | Ultrastructural study of adherence to and penetration of cultured cells by two invasive Escherichia coli strains isolated from infants with enteritis. | lld:pubmed |
| pubmed-article:6373610 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6373610 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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