| pubmed-article:6352503 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6352503 | lifeskim:mentions | umls-concept:C0042029 | lld:lifeskim |
| pubmed-article:6352503 | lifeskim:mentions | umls-concept:C0014834 | lld:lifeskim |
| pubmed-article:6352503 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:6352503 | lifeskim:mentions | umls-concept:C1522642 | lld:lifeskim |
| pubmed-article:6352503 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:6352503 | lifeskim:mentions | umls-concept:C0019053 | lld:lifeskim |
| pubmed-article:6352503 | lifeskim:mentions | umls-concept:C0600688 | lld:lifeskim |
| pubmed-article:6352503 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
| pubmed-article:6352503 | lifeskim:mentions | umls-concept:C1524003 | lld:lifeskim |
| pubmed-article:6352503 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6352503 | pubmed:dateCreated | 1983-11-23 | lld:pubmed |
| pubmed-article:6352503 | pubmed:abstractText | After intraperitoneal injection of mice with Escherichia coli strains isolated from patients with urinary tract infections, the mortality due to hemolytic (Hly+) and nonhemolytic (Hly-) isolates was 77 and 40%, respectively. Deletion of the chromosomal hemolysin (hly) determinant in an E. coli O6:K15:H31 urinary tract infection strain led to a significant reduction in toxicity for mice, and its reintroduction on a recombinant plasmid partially restored the original toxicity. Although introduction of the cloned plasmid pHly152-encoded hly determinant into the Hly- E. coli O6 mutant strain increased toxicity by only a marginal degree, transformation with the cloned chromosomal hly determinants from two E. coli strains of serotypes O18ac:K5:H- and O75:K95:H? resulted in markedly greater toxicity, even exceeding that of the original Hly+ E. coli O6 wild-type strain. | lld:pubmed |
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| pubmed-article:6352503 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6352503 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6352503 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:6352503 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6352503 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:6352503 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:6352503 | pubmed:author | pubmed-author:GoebelWW | lld:pubmed |
| pubmed-article:6352503 | pubmed:author | pubmed-author:HackerJJ | lld:pubmed |
| pubmed-article:6352503 | pubmed:author | pubmed-author:HofHH | lld:pubmed |
| pubmed-article:6352503 | pubmed:author | pubmed-author:HughesCC | lld:pubmed |
| pubmed-article:6352503 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6352503 | pubmed:volume | 42 | lld:pubmed |
| pubmed-article:6352503 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6352503 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6352503 | pubmed:pagination | 57-63 | lld:pubmed |
| pubmed-article:6352503 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6352503 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6352503 | pubmed:articleTitle | Cloned hemolysin genes from Escherichia coli that cause urinary tract infection determine different levels of toxicity in mice. | lld:pubmed |
| pubmed-article:6352503 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6352503 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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