pubmed-article:6329993 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6329993 | lifeskim:mentions | umls-concept:C0062523 | lld:lifeskim |
pubmed-article:6329993 | lifeskim:mentions | umls-concept:C0008111 | lld:lifeskim |
pubmed-article:6329993 | lifeskim:mentions | umls-concept:C0227525 | lld:lifeskim |
pubmed-article:6329993 | lifeskim:mentions | umls-concept:C0038528 | lld:lifeskim |
pubmed-article:6329993 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
pubmed-article:6329993 | lifeskim:mentions | umls-concept:C1264633 | lld:lifeskim |
pubmed-article:6329993 | lifeskim:mentions | umls-concept:C0475264 | lld:lifeskim |
pubmed-article:6329993 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:6329993 | pubmed:dateCreated | 1984-8-17 | lld:pubmed |
pubmed-article:6329993 | pubmed:abstractText | The localization of hepatitis A virus antigen to specific subcellular fractions of infected chimpanzee liver cells was studied by solid-phase radioimmunoassay following a mild subcellular fractionation procedure designed to separate various organelles from the cytosol and the nuclei. Most of the antigenic activity (93%) was evenly divided between the cytosol fraction and the microsomal suspension. Within the microsomal fraction, more than 75% of the detectable antigen was associated with the smooth endoplasmic reticulum. Less than 4% of the total antigenic activity was localized to the nucleus. These data provide additional evidence that replication of hepatitis A virus occurs primarily within the cytoplasm of the host cell in close association with cellular membranes, consistent with that observed for other members of the genus Enterovirus. | lld:pubmed |
pubmed-article:6329993 | pubmed:language | eng | lld:pubmed |
pubmed-article:6329993 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6329993 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6329993 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6329993 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6329993 | pubmed:issn | 0300-5526 | lld:pubmed |
pubmed-article:6329993 | pubmed:author | pubmed-author:HollingerF... | lld:pubmed |
pubmed-article:6329993 | pubmed:author | pubmed-author:MelnickJ LJL | lld:pubmed |
pubmed-article:6329993 | pubmed:author | pubmed-author:KhanN CNC | lld:pubmed |
pubmed-article:6329993 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6329993 | pubmed:volume | 21 | lld:pubmed |
pubmed-article:6329993 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6329993 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6329993 | pubmed:pagination | 187-94 | lld:pubmed |
pubmed-article:6329993 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:6329993 | pubmed:meshHeading | pubmed-meshheading:6329993-... | lld:pubmed |
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pubmed-article:6329993 | pubmed:meshHeading | pubmed-meshheading:6329993-... | lld:pubmed |
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pubmed-article:6329993 | pubmed:meshHeading | pubmed-meshheading:6329993-... | lld:pubmed |
pubmed-article:6329993 | pubmed:year | 1984 | lld:pubmed |
pubmed-article:6329993 | pubmed:articleTitle | Localization of hepatitis A virus antigen to specific subcellular fractions of hepatitis-A-infected chimpanzee liver cells. | lld:pubmed |
pubmed-article:6329993 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6329993 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |