Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:6325017rdf:typepubmed:Citationlld:pubmed
pubmed-article:6325017lifeskim:mentionsumls-concept:C0007634lld:lifeskim
pubmed-article:6325017lifeskim:mentionsumls-concept:C0034693lld:lifeskim
pubmed-article:6325017lifeskim:mentionsumls-concept:C0032016lld:lifeskim
pubmed-article:6325017lifeskim:mentionsumls-concept:C0232105lld:lifeskim
pubmed-article:6325017lifeskim:mentionsumls-concept:C0936012lld:lifeskim
pubmed-article:6325017lifeskim:mentionsumls-concept:C0392762lld:lifeskim
pubmed-article:6325017lifeskim:mentionsumls-concept:C0857121lld:lifeskim
pubmed-article:6325017pubmed:issue1lld:pubmed
pubmed-article:6325017pubmed:dateCreated1984-6-8lld:pubmed
pubmed-article:6325017pubmed:abstractTextACTH-immunoreactive cells in the anterior pituitary of 4-week-old spontaneously hypertensive rats (SHR) were studied with immunocytochemical and morphometric techniques. The results were compared with data from age-matched normotensive Wistar-Kyoto rats (WKY). No significant differences were found in volume density and average size of ACTH-immunoreactive cells between these two strains. However, SHR showed a significantly larger anterior lobe (2 P less than 0.01) than WKY, indicating that the total number of ACTH-immunoreactive cells in the anterior pituitary is greater in SHR than in WKY. These data are in agreement with radioimmunological determinations showing a significantly elevated content (2P less than 0.01) but only a moderately higher concentration (0.05 less than 2P less than 0.10) of ACTH in the anterior pituitary of SHR as compared to WKY. The present results suggest an enhanced availability of ACTH in the anterior pituitary of 4-week-old SHR, a fact which could explain the markedly enhanced stress-induced release of ACTH previously found in these animals. This study further supports the hypothesis that, among other factors, an instability of the hypothalamo-pituitary-adrenal axis may contribute to the development of genetically programmed hypertension.lld:pubmed
pubmed-article:6325017pubmed:languageenglld:pubmed
pubmed-article:6325017pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6325017pubmed:citationSubsetIMlld:pubmed
pubmed-article:6325017pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6325017pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6325017pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6325017pubmed:statusMEDLINElld:pubmed
pubmed-article:6325017pubmed:issn0302-766Xlld:pubmed
pubmed-article:6325017pubmed:authorpubmed-author:GirardJJlld:pubmed
pubmed-article:6325017pubmed:authorpubmed-author:BaumannJ BJBlld:pubmed
pubmed-article:6325017pubmed:authorpubmed-author:HeitzP UPUlld:pubmed
pubmed-article:6325017pubmed:authorpubmed-author:OberholzerMMlld:pubmed
pubmed-article:6325017pubmed:authorpubmed-author:HäuslerAAlld:pubmed
pubmed-article:6325017pubmed:issnTypePrintlld:pubmed
pubmed-article:6325017pubmed:volume236lld:pubmed
pubmed-article:6325017pubmed:ownerNLMlld:pubmed
pubmed-article:6325017pubmed:authorsCompleteYlld:pubmed
pubmed-article:6325017pubmed:pagination229-35lld:pubmed
pubmed-article:6325017pubmed:dateRevised2006-11-15lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:meshHeadingpubmed-meshheading:6325017-...lld:pubmed
pubmed-article:6325017pubmed:year1984lld:pubmed
pubmed-article:6325017pubmed:articleTitleQuantitative analysis of ACTH-immunoreactive cells in the anterior pituitary of young spontaneously hypertensive and normotensive rats.lld:pubmed
pubmed-article:6325017pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:6325017pubmed:publicationTypeComparative Studylld:pubmed