| pubmed-article:6302474 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6302474 | lifeskim:mentions | umls-concept:C0038975 | lld:lifeskim |
| pubmed-article:6302474 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:6302474 | lifeskim:mentions | umls-concept:C0041361 | lld:lifeskim |
| pubmed-article:6302474 | lifeskim:mentions | umls-concept:C0079866 | lld:lifeskim |
| pubmed-article:6302474 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:6302474 | pubmed:dateCreated | 1983-6-10 | lld:pubmed |
| pubmed-article:6302474 | pubmed:abstractText | We analyzed the mutation frequency to 8-azaguanine (8AZ) resistance in rat FR3T3 cells acutely infected with simian virus 40 wild type and tsA and early deletion mutants and in a series of temperature-sensitive (N) and temperature-insensitive (A) transformants derived from Chinese hamster lung (CHL) cells. Upon acute infection, the frequency of mutation to 8AZ resistance was raised at most by two- to eightfold over the spontaneous frequency, and it was independent of the presence of a functional 90,000-molecular-weight T antigen or 20,000-molecular-weight t antigen or both. Similarly, in the stable transformants of CHL cells, no correlation was found between functional T antigens and mutation to 8AZ resistance. It therefore seems unlikely that simian virus 40-induced transformation results from any mutagenic activity of this virus. | lld:pubmed |
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| pubmed-article:6302474 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6302474 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6302474 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6302474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6302474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6302474 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6302474 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:6302474 | pubmed:issn | 0270-7306 | lld:pubmed |
| pubmed-article:6302474 | pubmed:author | pubmed-author:MartinR GRG | lld:pubmed |
| pubmed-article:6302474 | pubmed:author | pubmed-author:Zannis-Hadjop... | lld:pubmed |
| pubmed-article:6302474 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6302474 | pubmed:volume | 3 | lld:pubmed |
| pubmed-article:6302474 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6302474 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6302474 | pubmed:pagination | 421-8 | lld:pubmed |
| pubmed-article:6302474 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6302474 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6302474 | pubmed:articleTitle | Relationship of simian virus 40 tumor antigens to virus-induced mutagenesis. | lld:pubmed |
| pubmed-article:6302474 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6302474 | lld:pubmed |
