| pubmed-article:6300572 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6300572 | lifeskim:mentions | umls-concept:C0026237 | lld:lifeskim |
| pubmed-article:6300572 | lifeskim:mentions | umls-concept:C1882598 | lld:lifeskim |
| pubmed-article:6300572 | lifeskim:mentions | umls-concept:C0244104 | lld:lifeskim |
| pubmed-article:6300572 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:6300572 | lifeskim:mentions | umls-concept:C0243144 | lld:lifeskim |
| pubmed-article:6300572 | lifeskim:mentions | umls-concept:C0443172 | lld:lifeskim |
| pubmed-article:6300572 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:6300572 | pubmed:dateCreated | 1983-5-5 | lld:pubmed |
| pubmed-article:6300572 | pubmed:abstractText | Changes in the uptake of pyruvate by nonsynaptic and synaptic mitochondria from brains of young adult and old rats were investigated. An age-dependent decrease in State 3 respiration in the presence of pyruvate plus malate as substrate was observed in cerebral mitochondrial populations but not in liver mitochondria. Addition of exogenous cytochrome c to nonsynaptic and synaptic mitochondria enhanced the rate of State 3 respiration but the age-dependent decrease in State 3 respiration persisted in both types of mitochondria. A decrease in the uptake of pyruvate as measured by the inhibitor-stop and rapid centrifugation techniques was observed in both nonsynaptic and synaptic mitochondria from 24-month-old rats compared to 3-month-old rats. The results suggest that the decrease in the uptake of pyruvate may be one of the factors responsible for the observed reduction in State 3 respiration in the presence of pyruvate plus malate by both nonsynaptic and synaptic mitochondria from brains of senescent rats compared to young adults. | lld:pubmed |
| pubmed-article:6300572 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6300572 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6300572 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6300572 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6300572 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6300572 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6300572 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6300572 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6300572 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6300572 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6300572 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:6300572 | pubmed:issn | 0047-6374 | lld:pubmed |
| pubmed-article:6300572 | pubmed:author | pubmed-author:DeshmukhD RDR | lld:pubmed |
| pubmed-article:6300572 | pubmed:author | pubmed-author:PatelM SMS | lld:pubmed |
| pubmed-article:6300572 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6300572 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:6300572 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6300572 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6300572 | pubmed:pagination | 343-51 | lld:pubmed |
| pubmed-article:6300572 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:meshHeading | pubmed-meshheading:6300572-... | lld:pubmed |
| pubmed-article:6300572 | pubmed:year | 1982 | lld:pubmed |
| pubmed-article:6300572 | pubmed:articleTitle | Age-dependent changes in pyruvate uptake by nonsynaptic and synaptic mitochondria from rat brain. | lld:pubmed |
| pubmed-article:6300572 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6300572 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:6300572 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:6300572 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6300572 | lld:pubmed |
