| pubmed-article:6293587 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6293587 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:6293587 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:6293587 | lifeskim:mentions | umls-concept:C1518997 | lld:lifeskim |
| pubmed-article:6293587 | lifeskim:mentions | umls-concept:C0449468 | lld:lifeskim |
| pubmed-article:6293587 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
| pubmed-article:6293587 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:6293587 | lifeskim:mentions | umls-concept:C1514485 | lld:lifeskim |
| pubmed-article:6293587 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:6293587 | pubmed:dateCreated | 1983-2-25 | lld:pubmed |
| pubmed-article:6293587 | pubmed:abstractText | Human peripheral blood lymphocytes exposed to hypotonic media (Ca/Mg-free, room temp.) first swell and then shrink. This shrinking response is characterized by a simple exponential with a half-time of 1.44 +/- 0.60 min (n = 11) and its extent but not the half-time for a given hypotonicity is influenced by [K+]0. Using K-selective electrodes, we observe a change in [K+]0 when cells are diluted into hypotonic media. A half-time of 1.55 +/- 0.06 min (n = 4) was obtained. A similar half-time was obtained by assay of total cell K using atomic absorption spectroscopy. At all osmolarities [K+]i was decreased from control values and was constant as [K+]0 was increased. Short-term incubation with ouabain (10(-4) M) had no effect. Decreasing osmolarities progressively inhibited phytohemagglutinin-stimulated DNA synthesis, yet cell number and viability remained unaltered. Our evidence indicates that the volume response is mediated by a change in the passive permeability of the plasma membrane to K and/or to the accompanying anions, and that the consequently volume-adapted cells are growth-inhibited. | lld:pubmed |
| pubmed-article:6293587 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293587 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293587 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6293587 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293587 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6293587 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293587 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293587 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293587 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6293587 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:6293587 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:6293587 | pubmed:author | pubmed-author:DeutschCC | lld:pubmed |
| pubmed-article:6293587 | pubmed:author | pubmed-author:GoldsteinPP | lld:pubmed |
| pubmed-article:6293587 | pubmed:author | pubmed-author:SlaterLL | lld:pubmed |
| pubmed-article:6293587 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6293587 | pubmed:day | 17 | lld:pubmed |
| pubmed-article:6293587 | pubmed:volume | 721 | lld:pubmed |
| pubmed-article:6293587 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6293587 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6293587 | pubmed:pagination | 262-7 | lld:pubmed |
| pubmed-article:6293587 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:6293587 | pubmed:meshHeading | pubmed-meshheading:6293587-... | lld:pubmed |
| pubmed-article:6293587 | pubmed:meshHeading | pubmed-meshheading:6293587-... | lld:pubmed |
| pubmed-article:6293587 | pubmed:meshHeading | pubmed-meshheading:6293587-... | lld:pubmed |
| pubmed-article:6293587 | pubmed:meshHeading | pubmed-meshheading:6293587-... | lld:pubmed |
| pubmed-article:6293587 | pubmed:meshHeading | pubmed-meshheading:6293587-... | lld:pubmed |
| pubmed-article:6293587 | pubmed:meshHeading | pubmed-meshheading:6293587-... | lld:pubmed |
| pubmed-article:6293587 | pubmed:meshHeading | pubmed-meshheading:6293587-... | lld:pubmed |
| pubmed-article:6293587 | pubmed:meshHeading | pubmed-meshheading:6293587-... | lld:pubmed |
| pubmed-article:6293587 | pubmed:meshHeading | pubmed-meshheading:6293587-... | lld:pubmed |
| pubmed-article:6293587 | pubmed:meshHeading | pubmed-meshheading:6293587-... | lld:pubmed |
| pubmed-article:6293587 | pubmed:year | 1982 | lld:pubmed |
| pubmed-article:6293587 | pubmed:articleTitle | Volume regulation of human peripheral blood lymphocytes and stimulated proliferation of volume-adapted cells. | lld:pubmed |
| pubmed-article:6293587 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6293587 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6293587 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6293587 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6293587 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6293587 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6293587 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6293587 | lld:pubmed |
