pubmed-article:627724 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:627724 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
pubmed-article:627724 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:627724 | lifeskim:mentions | umls-concept:C0278803 | lld:lifeskim |
pubmed-article:627724 | lifeskim:mentions | umls-concept:C0301896 | lld:lifeskim |
pubmed-article:627724 | lifeskim:mentions | umls-concept:C2828366 | lld:lifeskim |
pubmed-article:627724 | lifeskim:mentions | umls-concept:C1705851 | lld:lifeskim |
pubmed-article:627724 | lifeskim:mentions | umls-concept:C0332206 | lld:lifeskim |
pubmed-article:627724 | lifeskim:mentions | umls-concept:C1555707 | lld:lifeskim |
pubmed-article:627724 | lifeskim:mentions | umls-concept:C2752151 | lld:lifeskim |
pubmed-article:627724 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:627724 | pubmed:dateCreated | 1978-4-26 | lld:pubmed |
pubmed-article:627724 | pubmed:abstractText | Hypertonic salt extracts (3 M KCl) of x-irradiation-induced Holtzman rat small bowel adenocarcinomas blocked the in vitro destruction of allogeneic cultured cells of this malignancy by sensitized lymphoid cells obtained from tumor-bearing animals. The protective effect were mediated by a blocking action at both the effector and the target cell level. The extracts were separated into 50% ammonium sulfate soluble and insoluble fractions with the soluble fraction being more effective in blocking the cytotoxic responses through interaction with the lymphoid cells whereas the insoluble one had a greater effect upon tumor target cells. Associated with both fractions was the oncofetal glycoprotein previously identified with the cellular membrane of this x-ray-induced malignancy. Immunoglobulins were identified with insoluble fraction; some were able to bind the oncofetal protein, thus clasifying it as a fetal antigen. The protective effects of the soluble fraction and this neoantigen were found to be citric acid labile, whereas the effects due to the insoluble fraction were unchanged. | lld:pubmed |
pubmed-article:627724 | pubmed:language | eng | lld:pubmed |
pubmed-article:627724 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:627724 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:627724 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:627724 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:627724 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:627724 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:627724 | pubmed:month | Jan | lld:pubmed |
pubmed-article:627724 | pubmed:issn | 0022-1767 | lld:pubmed |
pubmed-article:627724 | pubmed:author | pubmed-author:OsborneJ WJW | lld:pubmed |
pubmed-article:627724 | pubmed:author | pubmed-author:StevensR HRH | lld:pubmed |
pubmed-article:627724 | pubmed:author | pubmed-author:LawsonA JAJ | lld:pubmed |
pubmed-article:627724 | pubmed:author | pubmed-author:BrooksG PGP | lld:pubmed |
pubmed-article:627724 | pubmed:author | pubmed-author:HoffmanK LKL | lld:pubmed |
pubmed-article:627724 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:627724 | pubmed:volume | 120 | lld:pubmed |
pubmed-article:627724 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:627724 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:627724 | pubmed:pagination | 335-9 | lld:pubmed |
pubmed-article:627724 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:627724 | pubmed:meshHeading | pubmed-meshheading:627724-C... | lld:pubmed |
pubmed-article:627724 | pubmed:year | 1978 | lld:pubmed |
pubmed-article:627724 | pubmed:articleTitle | Lymphocyte cytotoxicity in x-irradiation-induced rat small bowel adenocarcinoma. III. Blocking by 3 M KCL extract. | lld:pubmed |
pubmed-article:627724 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:627724 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:627724 | lld:pubmed |