| pubmed-article:6262985 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6262985 | lifeskim:mentions | umls-concept:C0030274 | lld:lifeskim |
| pubmed-article:6262985 | lifeskim:mentions | umls-concept:C0005528 | lld:lifeskim |
| pubmed-article:6262985 | lifeskim:mentions | umls-concept:C0017725 | lld:lifeskim |
| pubmed-article:6262985 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:6262985 | lifeskim:mentions | umls-concept:C2245393 | lld:lifeskim |
| pubmed-article:6262985 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:6262985 | pubmed:dateCreated | 1981-7-9 | lld:pubmed |
| pubmed-article:6262985 | pubmed:abstractText | The role of Ca2+ in the regulation of insulin secretion was evaluated using beta-cell-rich pancreatic islets isolated from ob/ob-mice. The glucose stimulation of the secretory activity is supposed to result from accumulation of Ca2+ in the submembrane cytoplasmic space. It is likely that this process reflects the balance between increased entry of Ca2+ into the beta-cells and an enhanced sequestration of Ca2+ in the organelle sinks. The proposed model can explain the cAMP potentiation of glucose-stimulated insulin release with suppression of the mitochondrial Ca2+ uptake. Furthermore, differences in the Ca2+ buffering capacity of the secretory granules may account for other characteristic features of glucose-stimulated insulin release, in particular its biphasic nature and sensitivity to suppression on withdrawal of nutrients. | lld:pubmed |
| pubmed-article:6262985 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6262985 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6262985 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6262985 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6262985 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6262985 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6262985 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6262985 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6262985 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6262985 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6262985 | pubmed:issn | 0300-9734 | lld:pubmed |
| pubmed-article:6262985 | pubmed:author | pubmed-author:AnderssonTT | lld:pubmed |
| pubmed-article:6262985 | pubmed:author | pubmed-author:HellmanBB | lld:pubmed |
| pubmed-article:6262985 | pubmed:author | pubmed-author:GylfeEE | lld:pubmed |
| pubmed-article:6262985 | pubmed:author | pubmed-author:BerggrenP OPO | lld:pubmed |
| pubmed-article:6262985 | pubmed:author | pubmed-author:AbrahamssonHH | lld:pubmed |
| pubmed-article:6262985 | pubmed:author | pubmed-author:RorsmanPP | lld:pubmed |
| pubmed-article:6262985 | pubmed:author | pubmed-author:BetsholtzCC | lld:pubmed |
| pubmed-article:6262985 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6262985 | pubmed:volume | 85 | lld:pubmed |
| pubmed-article:6262985 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6262985 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6262985 | pubmed:pagination | 321-9 | lld:pubmed |
| pubmed-article:6262985 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:6262985 | pubmed:meshHeading | pubmed-meshheading:6262985-... | lld:pubmed |
| pubmed-article:6262985 | pubmed:meshHeading | pubmed-meshheading:6262985-... | lld:pubmed |
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| pubmed-article:6262985 | pubmed:meshHeading | pubmed-meshheading:6262985-... | lld:pubmed |
| pubmed-article:6262985 | pubmed:meshHeading | pubmed-meshheading:6262985-... | lld:pubmed |
| pubmed-article:6262985 | pubmed:meshHeading | pubmed-meshheading:6262985-... | lld:pubmed |
| pubmed-article:6262985 | pubmed:meshHeading | pubmed-meshheading:6262985-... | lld:pubmed |
| pubmed-article:6262985 | pubmed:meshHeading | pubmed-meshheading:6262985-... | lld:pubmed |
| pubmed-article:6262985 | pubmed:meshHeading | pubmed-meshheading:6262985-... | lld:pubmed |
| pubmed-article:6262985 | pubmed:meshHeading | pubmed-meshheading:6262985-... | lld:pubmed |
| pubmed-article:6262985 | pubmed:meshHeading | pubmed-meshheading:6262985-... | lld:pubmed |
| pubmed-article:6262985 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:6262985 | pubmed:articleTitle | Ca2+ transport in pancreatic beta-cells during glucose stimulation of insulin secretion. | lld:pubmed |
| pubmed-article:6262985 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6262985 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6262985 | lld:pubmed |
