| pubmed-article:6256112 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6256112 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:6256112 | lifeskim:mentions | umls-concept:C0014776 | lld:lifeskim |
| pubmed-article:6256112 | lifeskim:mentions | umls-concept:C0155616 | lld:lifeskim |
| pubmed-article:6256112 | lifeskim:mentions | umls-concept:C1148926 | lld:lifeskim |
| pubmed-article:6256112 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
| pubmed-article:6256112 | pubmed:dateCreated | 1981-3-27 | lld:pubmed |
| pubmed-article:6256112 | pubmed:abstractText | 1. We have investigated the function of the Na+-K+ pump in the erythrocytes of patients with various types of hypertension by measuring the activity of ouabain-sensitive Na+-K+-dependent ATPase and ouabain-insensitive ATPase in the erythrocyte ghosts of these patients. 2. Mean Na+-K+-ATPase activity was increased threefold in six patients with Cushing's syndrome and hypertension (0.985 +/- SD 0.288 mumol of phosphate h-1 mg-1) compared with that in 49 control subjects (0.334 +/- 0.147 mumol of phosphate h-1 mg-1) (P < 0.0025), but not in four patients with primary aldosteronism (0.278 +/- 0.108 mumol of phosphate h-1 mg-1). 3. Na+-K+-ATPase activity slightly exceeded the control range in 57 patients with primary hypertension (0.410 +/- 0.245 mumol of phosphate h-1 mg-1; P < 0.025) and in 12 patients with renal hypertension (0.475 +/- 0.250 mumol of phosphate h-1 mg-1) (P < 0.025). 4. There was no difference in ouabain-insensitive ATPase between the controls and the different types of hypertension. 5. The data support the hypothesis of an activation of the Na+ pump in patients with glucocorticoid excess. This helps to explain previous observations of a redistribution of sodium and water to the extracellular compartment in experimental glucocorticoid-induced hypertension. | lld:pubmed |
| pubmed-article:6256112 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6256112 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6256112 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6256112 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6256112 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6256112 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6256112 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6256112 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:6256112 | pubmed:issn | 0143-5221 | lld:pubmed |
| pubmed-article:6256112 | pubmed:author | pubmed-author:HummerichWW | lld:pubmed |
| pubmed-article:6256112 | pubmed:author | pubmed-author:KaufmannWW | lld:pubmed |
| pubmed-article:6256112 | pubmed:author | pubmed-author:HelberAA | lld:pubmed |
| pubmed-article:6256112 | pubmed:author | pubmed-author:WambachGG | lld:pubmed |
| pubmed-article:6256112 | pubmed:author | pubmed-author:KonradsAA | lld:pubmed |
| pubmed-article:6256112 | pubmed:author | pubmed-author:BönnerGG | lld:pubmed |
| pubmed-article:6256112 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6256112 | pubmed:volume | 59 Suppl 6 | lld:pubmed |
| pubmed-article:6256112 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6256112 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6256112 | pubmed:pagination | 183s-185s | lld:pubmed |
| pubmed-article:6256112 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:meshHeading | pubmed-meshheading:6256112-... | lld:pubmed |
| pubmed-article:6256112 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:6256112 | pubmed:articleTitle | Sodium-potassium-dependent ATPase activity in erythrocyte ghosts of patients with primary and secondary hypertension. | lld:pubmed |
| pubmed-article:6256112 | pubmed:publicationType | Journal Article | lld:pubmed |
