| pubmed-article:6253081 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6253081 | lifeskim:mentions | umls-concept:C0034865 | lld:lifeskim |
| pubmed-article:6253081 | lifeskim:mentions | umls-concept:C0043393 | lld:lifeskim |
| pubmed-article:6253081 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:6253081 | lifeskim:mentions | umls-concept:C1709305 | lld:lifeskim |
| pubmed-article:6253081 | lifeskim:mentions | umls-concept:C0439836 | lld:lifeskim |
| pubmed-article:6253081 | pubmed:issue | 1 Pt 1 | lld:pubmed |
| pubmed-article:6253081 | pubmed:dateCreated | 1981-1-16 | lld:pubmed |
| pubmed-article:6253081 | pubmed:abstractText | The switching of yeast mating-type alleles involves a transposition of a copy of a sequence from HML or HMR to replace the sequences at MAT. Using diploid strains of yeast we have discovered that about 1% of the homothalic conversions of MAT alleles are accompanied by large intrachromosomal rearrangements. These rearrangements are highly specific fusions of part of MAT either with HMR (to produce a deficiency ring chromosome). We conclude that the mechanism of MAT conversions involves a highly specific pairing between the homologous sequences at MAT and the donor genes HML or HMR followed by a specialized gene conversion event, in which the original allele is replaced by a sequence copied from HMR or HML. At about a 1% frequency conversion of the MAT locus is accompanied by a reciprocal recombination event that results in an intrachromosomal deletion. This same preferential pairing is reflected in a high frequency (> 10(-3)) of site-specific mitotic recombination between MAT alleles on differenat chromosomes. A gene conversion model also allows us to explain the "illegal" transpositions of MAT alleles to HMR or HML that occur when normal excision of MAT is prevented. | lld:pubmed |
| pubmed-article:6253081 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6253081 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6253081 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6253081 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6253081 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6253081 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6253081 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6253081 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:6253081 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:6253081 | pubmed:author | pubmed-author:HaberJ EJE | lld:pubmed |
| pubmed-article:6253081 | pubmed:author | pubmed-author:McCuskerJ HJH | lld:pubmed |
| pubmed-article:6253081 | pubmed:author | pubmed-author:RogersD TDT | lld:pubmed |
| pubmed-article:6253081 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6253081 | pubmed:volume | 22 | lld:pubmed |
| pubmed-article:6253081 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6253081 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6253081 | pubmed:pagination | 277-89 | lld:pubmed |
| pubmed-article:6253081 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6253081 | pubmed:meshHeading | pubmed-meshheading:6253081-... | lld:pubmed |
| pubmed-article:6253081 | pubmed:meshHeading | pubmed-meshheading:6253081-... | lld:pubmed |
| pubmed-article:6253081 | pubmed:meshHeading | pubmed-meshheading:6253081-... | lld:pubmed |
| pubmed-article:6253081 | pubmed:meshHeading | pubmed-meshheading:6253081-... | lld:pubmed |
| pubmed-article:6253081 | pubmed:meshHeading | pubmed-meshheading:6253081-... | lld:pubmed |
| pubmed-article:6253081 | pubmed:meshHeading | pubmed-meshheading:6253081-... | lld:pubmed |
| pubmed-article:6253081 | pubmed:meshHeading | pubmed-meshheading:6253081-... | lld:pubmed |
| pubmed-article:6253081 | pubmed:meshHeading | pubmed-meshheading:6253081-... | lld:pubmed |
| pubmed-article:6253081 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:6253081 | pubmed:articleTitle | Homothallic conversions of yeast mating-type genes occur by intrachromosomal recombination. | lld:pubmed |
| pubmed-article:6253081 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6253081 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6253081 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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