pubmed-article:6248509 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6248509 | lifeskim:mentions | umls-concept:C0034493 | lld:lifeskim |
pubmed-article:6248509 | lifeskim:mentions | umls-concept:C0027950 | lld:lifeskim |
pubmed-article:6248509 | lifeskim:mentions | umls-concept:C0085236 | lld:lifeskim |
pubmed-article:6248509 | lifeskim:mentions | umls-concept:C0020281 | lld:lifeskim |
pubmed-article:6248509 | lifeskim:mentions | umls-concept:C0009491 | lld:lifeskim |
pubmed-article:6248509 | lifeskim:mentions | umls-concept:C0079411 | lld:lifeskim |
pubmed-article:6248509 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:6248509 | pubmed:dateCreated | 1980-9-28 | lld:pubmed |
pubmed-article:6248509 | pubmed:abstractText | The oxidative metabolism of rabbit alveolar macrophages (A-MO) was compared with that of rabbit polymorphonuclear leukocytes (PMN) with respect to H2O2 generation by intact cells or subcellular fractions. Rabbit PMN exhibited an increase in the oxygen uptake and a marked release of H2O2 upon addition of heat-killed E. coli in the presence and absence of opsonin. However, rabbit A-MO exhibited an increase in the oxygen uptake upon addition of E. coli only in the presence of anti-E. coli serum as an opsonin, whereas a very small amount of H2O2 release was observed during ingestion of the opsonized E. coli. The generation of O2- and H2O2 by a granule-rich fraction isolated from phagocytosing PMN was larger than that by a similar fraction isolated from resting PMN. However, there was no significant difference in O2- and H2O2 generation by the granule fractions between phagocytosing and resting A-MO in the presence of either NADH or NADPH. In contrast to the granule fraction of rabbit PMN, the O2- and H2O2 generating activities in the A-MO granule fraction were higher in the presence of NADH than in the presence of NADPH. The rates of NADH and NADPH oxidation by both A-MO and PMN granule fractions were measured with and without addition of Mn2+ to the assay medium. The effect of Mn2+ on the NAD(P)H oxidase was found to differ between rabbit A-MO and PMN. | lld:pubmed |
pubmed-article:6248509 | pubmed:language | eng | lld:pubmed |
pubmed-article:6248509 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6248509 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6248509 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6248509 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6248509 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6248509 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6248509 | pubmed:month | May | lld:pubmed |
pubmed-article:6248509 | pubmed:issn | 0021-924X | lld:pubmed |
pubmed-article:6248509 | pubmed:author | pubmed-author:KakinumaKK | lld:pubmed |
pubmed-article:6248509 | pubmed:author | pubmed-author:YamaguchiTT | lld:pubmed |
pubmed-article:6248509 | pubmed:author | pubmed-author:KanedaMM | lld:pubmed |
pubmed-article:6248509 | pubmed:author | pubmed-author:ShimadaKK | lld:pubmed |
pubmed-article:6248509 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6248509 | pubmed:volume | 87 | lld:pubmed |
pubmed-article:6248509 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6248509 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6248509 | pubmed:pagination | 1449-55 | lld:pubmed |
pubmed-article:6248509 | pubmed:dateRevised | 2007-12-19 | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:meshHeading | pubmed-meshheading:6248509-... | lld:pubmed |
pubmed-article:6248509 | pubmed:year | 1980 | lld:pubmed |
pubmed-article:6248509 | pubmed:articleTitle | Comparative studies on alveolar macrophages and polymorphonuclear leukocytes. I. H2O2 and O2- generation by rabbit alveolar macrophages. | lld:pubmed |
pubmed-article:6248509 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6248509 | pubmed:publicationType | Comparative Study | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6248509 | lld:pubmed |