| pubmed-article:6245237 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6245237 | lifeskim:mentions | umls-concept:C0000742 | lld:lifeskim |
| pubmed-article:6245237 | lifeskim:mentions | umls-concept:C0567416 | lld:lifeskim |
| pubmed-article:6245237 | lifeskim:mentions | umls-concept:C0596988 | lld:lifeskim |
| pubmed-article:6245237 | lifeskim:mentions | umls-concept:C1417754 | lld:lifeskim |
| pubmed-article:6245237 | lifeskim:mentions | umls-concept:C1515926 | lld:lifeskim |
| pubmed-article:6245237 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6245237 | pubmed:dateCreated | 1980-6-25 | lld:pubmed |
| pubmed-article:6245237 | pubmed:abstractText | Abelson murine leukemia virus (A-MuLV) is a replication-defective virus that transforms both fibroblasts and hematopoietic cells in vitro. The virus encodes a 120,000-molecular-weight protein (P120) that is composed of Moloney murine leukemia virus-derived gag gene sequences and A-MuLV--specific sequences. This protein is the only A-MuLV--encoded protein that has been detected, and thus P120 is a candidate for the transforming protein of A-MuLV. We now report isolation and characterization of three new A-MuLV isolates that do not synthesize P120 but do produce analogous proteins of larger (160,000 molecular weight) and smaller (100,000 and 90,000 molecular weight) size. All of these A-MuLV isolates transform fibroblasts and lymphoid cells in vitro. Because the different A-MuLV proteins vary in the A-MuLV--specific region of the molecule, these variants may set a maximum limit on the size of the A-MuLV transforming protein. | lld:pubmed |
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| pubmed-article:6245237 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:6245237 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:6245237 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6245237 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:6245237 | pubmed:issn | 0022-538X | lld:pubmed |
| pubmed-article:6245237 | pubmed:author | pubmed-author:WitteO NON | lld:pubmed |
| pubmed-article:6245237 | pubmed:author | pubmed-author:RosenbergNN | lld:pubmed |
| pubmed-article:6245237 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6245237 | pubmed:volume | 33 | lld:pubmed |
| pubmed-article:6245237 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6245237 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6245237 | pubmed:pagination | 340-8 | lld:pubmed |
| pubmed-article:6245237 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6245237 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:6245237 | pubmed:articleTitle | Abelson murine leukemia virus mutants with alterations in the virus-specific P120 molecule. | lld:pubmed |
| pubmed-article:6245237 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6245237 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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