| pubmed-article:6231856 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6231856 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:6231856 | lifeskim:mentions | umls-concept:C0002874 | lld:lifeskim |
| pubmed-article:6231856 | lifeskim:mentions | umls-concept:C0079720 | lld:lifeskim |
| pubmed-article:6231856 | lifeskim:mentions | umls-concept:C1304884 | lld:lifeskim |
| pubmed-article:6231856 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:6231856 | pubmed:dateCreated | 1984-5-10 | lld:pubmed |
| pubmed-article:6231856 | pubmed:abstractText | Lymphocyte subsets were enumerated in a group of 31 patients with aplastic anemia. Abnormal numbers of immunoregulatory T-cells were found in some patients: 26% of them showed a reversed helper/suppressor ratio. Seven of 18 patients showed significantly decreased proliferation in response to PWM; this hyporesponsiveness was present in 75% of patients with a reversed helper/suppressor ratio and in 10% of those with a normal helper/suppressor ratio (R = 0.66, P = 0.008). Eight of 18 patients showed suppressor activity over PWM-induced allogeneic cell proliferation. This suppressive activity did not correlate with T-cell phenotype. Of the patients with a low number of T-cells, 73% had responded to treatment, whereas of those patients with a normal number of T-cells, 26% had responded (P = 0.016). The results are consistent with abnormal immune response in selected patients with aplastic anemia, and suggest a possible influence of T-cells on disease process. | lld:pubmed |
| pubmed-article:6231856 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6231856 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6231856 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6231856 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6231856 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6231856 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6231856 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:6231856 | pubmed:issn | 0361-8609 | lld:pubmed |
| pubmed-article:6231856 | pubmed:author | pubmed-author:GreippP RPR | lld:pubmed |
| pubmed-article:6231856 | pubmed:author | pubmed-author:KatzmannJ AJA | lld:pubmed |
| pubmed-article:6231856 | pubmed:author | pubmed-author:Ruiz-Argüelle... | lld:pubmed |
| pubmed-article:6231856 | pubmed:author | pubmed-author:Marín-LópezAA | lld:pubmed |
| pubmed-article:6231856 | pubmed:author | pubmed-author:González-Llav... | lld:pubmed |
| pubmed-article:6231856 | pubmed:author | pubmed-author:Cano-Castella... | lld:pubmed |
| pubmed-article:6231856 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6231856 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:6231856 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6231856 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6231856 | pubmed:pagination | 267-75 | lld:pubmed |
| pubmed-article:6231856 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:meshHeading | pubmed-meshheading:6231856-... | lld:pubmed |
| pubmed-article:6231856 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6231856 | pubmed:articleTitle | Lymphocyte subsets in patients with aplastic anemia. | lld:pubmed |
| pubmed-article:6231856 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6231856 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
