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pubmed-article:6215856pubmed:abstractTextThe niacin metabolites N1-methyl-2-pyridone-5-carboxamide (2-PYR) and N1-methylnicotinamide (N-MN) have been quantified in human urine using isocratic reversed-phase high-performance liquid chromatography with ultraviolet detection after a simple anion-exchange clean-up procedure. The coefficients of variation (%) of the method for 2-PYR and N-MN were 6.3 and 6.8, respectively, and the limits of detection (mg/1 urine) were 0.05 for 2-PYR and 0.20 for N-MN. Results by this method compared favorably with those obtained by established techniques. It is a straight forward, rapid, and sensitive procedure for the assessment of niacin status.lld:pubmed
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pubmed-article:6215856pubmed:pagination926-30lld:pubmed
pubmed-article:6215856pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:6215856pubmed:articleTitleQuantitation of urinary niacin metabolites by reversed-phase liquid chromatography.lld:pubmed
pubmed-article:6215856pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:6215856pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:6215856pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed