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pubmed-article:62112pubmed:abstractTextOf 26 patients with intrinsic asthma, 21 (81%) were homozygous for the histocompatibility antigen HLA-W6. Also, half the patients had complement defects, in particular low levels of C2. This is the first indication of a strong genetic component in intrinsic asthma, apart from that already known from family studies. These findings suggest that intrinsic asthma may be a recessive disease.lld:pubmed
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pubmed-article:62112pubmed:articleTitle80% of patients with intrinsic asthma are homozygous for HLA W6. Is intrinsic asthma a recessive disease?lld:pubmed
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