| pubmed-article:6188628 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6188628 | lifeskim:mentions | umls-concept:C1521751 | lld:lifeskim |
| pubmed-article:6188628 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:6188628 | lifeskim:mentions | umls-concept:C0003316 | lld:lifeskim |
| pubmed-article:6188628 | lifeskim:mentions | umls-concept:C0580836 | lld:lifeskim |
| pubmed-article:6188628 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:6188628 | pubmed:dateCreated | 1983-6-10 | lld:pubmed |
| pubmed-article:6188628 | pubmed:abstractText | Antigenic differences between lymphocytes from young and old female C57BL/6 mice were studied using 3 techniques. In one-way mixed lymphocyte reactions significant responses were obtained in 7.7% of the young leads to young combinations, 13.5% of the young leads to old, 18.2% of the old leads to young and 23.7% of the old leads to old. Polyethylene glycol enhanced the weak syngeneic MLR responses in all groups. Young anti-old antiserum was raised in young animals by injecting with lymphoid cells from old mice. The serum was cytotoxic to spleen cells from 5 of 6 old mice aged in animal facilities at University of Alabama in Birmingham and from 2 of 12 mice aged at Charles River. Lymphocytes from young mice were sensitized to old lymphocytes in a mixed lymphocyte culture and their cytotoxicity toward old cells measured in a chromium-release assay. No cytotoxicity was observed with sensitized lymphocytes from 5 young mice under various conditions. These results do not support the hypothesis that altered anti-genic determinants are always or even usually present on the lymphocytes of old mice. | lld:pubmed |
| pubmed-article:6188628 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6188628 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6188628 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6188628 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6188628 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6188628 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6188628 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6188628 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6188628 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6188628 | pubmed:issn | 0531-5565 | lld:pubmed |
| pubmed-article:6188628 | pubmed:author | pubmed-author:HiramotoR NRN | lld:pubmed |
| pubmed-article:6188628 | pubmed:author | pubmed-author:GhantaV KVK | lld:pubmed |
| pubmed-article:6188628 | pubmed:author | pubmed-author:GolczewskiJ... | lld:pubmed |
| pubmed-article:6188628 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6188628 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:6188628 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6188628 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6188628 | pubmed:pagination | 375-81 | lld:pubmed |
| pubmed-article:6188628 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:6188628 | pubmed:meshHeading | pubmed-meshheading:6188628-... | lld:pubmed |
| pubmed-article:6188628 | pubmed:meshHeading | pubmed-meshheading:6188628-... | lld:pubmed |
| pubmed-article:6188628 | pubmed:meshHeading | pubmed-meshheading:6188628-... | lld:pubmed |
| pubmed-article:6188628 | pubmed:meshHeading | pubmed-meshheading:6188628-... | lld:pubmed |
| pubmed-article:6188628 | pubmed:meshHeading | pubmed-meshheading:6188628-... | lld:pubmed |
| pubmed-article:6188628 | pubmed:meshHeading | pubmed-meshheading:6188628-... | lld:pubmed |
| pubmed-article:6188628 | pubmed:meshHeading | pubmed-meshheading:6188628-... | lld:pubmed |
| pubmed-article:6188628 | pubmed:meshHeading | pubmed-meshheading:6188628-... | lld:pubmed |
| pubmed-article:6188628 | pubmed:meshHeading | pubmed-meshheading:6188628-... | lld:pubmed |
| pubmed-article:6188628 | pubmed:meshHeading | pubmed-meshheading:6188628-... | lld:pubmed |
| pubmed-article:6188628 | pubmed:year | 1982 | lld:pubmed |
| pubmed-article:6188628 | pubmed:articleTitle | Antigenic determinants on lymphocytes from young and old C57BL/6 mice. | lld:pubmed |
| pubmed-article:6188628 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6188628 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
