| pubmed-article:6181723 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6181723 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:6181723 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:6181723 | lifeskim:mentions | umls-concept:C0034069 | lld:lifeskim |
| pubmed-article:6181723 | lifeskim:mentions | umls-concept:C0178539 | lld:lifeskim |
| pubmed-article:6181723 | lifeskim:mentions | umls-concept:C0006279 | lld:lifeskim |
| pubmed-article:6181723 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:6181723 | lifeskim:mentions | umls-concept:C1306673 | lld:lifeskim |
| pubmed-article:6181723 | lifeskim:mentions | umls-concept:C0443199 | lld:lifeskim |
| pubmed-article:6181723 | lifeskim:mentions | umls-concept:C1301820 | lld:lifeskim |
| pubmed-article:6181723 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:6181723 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:6181723 | pubmed:dateCreated | 1982-12-3 | lld:pubmed |
| pubmed-article:6181723 | pubmed:abstractText | The purpose of this study was to analyze the cellular components of bronchoalveolar lavage fluid throughout the development of bleomycin-induced pulmonary fibrosis in the rat. Animals were killed and lavaged at various times after the administration of a single intratracheal injection of bleomycin. The results demonstrate that a significant influx of inflammatory cells appear in the lavage fluid as early as Day 1 after bleomycin treatment. Polymorphonuclear leukocytes are the first cells to appear and significant concentrations persist for as long as 1 month after bleomycin treatment. There is a very transient yet significant influx of eosinophils on Day 7 after bleomycin treatment. Lymphocytes are present from 3 to 14 days after bleomycin treatment; greater than 97% are T-cells and less than 3% are B-cells. There is a 1:1 ratio of W3/25+ cells (helper cell activity) to OX8+ cells (suppressor cell activity) comprising the lymphocyte population. The blood and lymphoid tissue of these animals contain a normal 2:1 ratio of these subsets. The data demonstrate that specific T-cell populations are present in the air spaces of the lung in response to bleomycin-induced pulmonary fibrosis in this model. | lld:pubmed |
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| pubmed-article:6181723 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6181723 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6181723 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6181723 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:6181723 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6181723 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6181723 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:6181723 | pubmed:issn | 0003-0805 | lld:pubmed |
| pubmed-article:6181723 | pubmed:author | pubmed-author:ThrallR SRS | lld:pubmed |
| pubmed-article:6181723 | pubmed:author | pubmed-author:BartonR WRW | lld:pubmed |
| pubmed-article:6181723 | pubmed:author | pubmed-author:SulavikS BSB | lld:pubmed |
| pubmed-article:6181723 | pubmed:author | pubmed-author:D'AmatoD ADA | lld:pubmed |
| pubmed-article:6181723 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6181723 | pubmed:volume | 126 | lld:pubmed |
| pubmed-article:6181723 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6181723 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6181723 | pubmed:pagination | 488-92 | lld:pubmed |
| pubmed-article:6181723 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:6181723 | pubmed:year | 1982 | lld:pubmed |
| pubmed-article:6181723 | pubmed:articleTitle | Differential cellular analysis of bronchoalveolar lavage fluid obtained at various stages during the development of bleomycin-induced pulmonary fibrosis in the rat. | lld:pubmed |
| pubmed-article:6181723 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6181723 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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