| pubmed-article:6166672 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C1513095 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0019628 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0021747 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0041361 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0024348 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0443199 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0439662 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0127400 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:6166672 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:6166672 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:6166672 | pubmed:dateCreated | 1981-9-15 | lld:pubmed |
| pubmed-article:6166672 | pubmed:abstractText | Incubation of cultured human melanoma cells with human leukocyte interferon did not change the expression of melanoma-associated antigens (MAA) recognized by monoclonal antibodies and of Ia-like antigens but significantly increased the expression of HLA-A,B antigens and of beta 2-microglobulin (beta 2-mu). The effect is dependent on the dose of interferon and on the incubation time. Interferon-treated melanoma cells showed an increased susceptibility to lysis mediated by monoclonal antibodies to HLA-A,B antigens and to human beta 2-mu; on the other hand, interferon-treated melanoma cells did not change in their susceptibility to murine natural killer (NK) cell lysis and to immune lysis mediated by monoclonal antibodies to MAA and to Ia-like antigens, and they displayed a reduced susceptibility to human NK cell lysis. Therefore, the increased susceptibility of interferon-treated melanoma cells to lysis mediated by anti HLA-A,B and anti beta 2-mu monoclonal antibodies is likely to reflect the increase in cell surface expression of the corresponding antigens. | lld:pubmed |
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| pubmed-article:6166672 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6166672 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6166672 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:6166672 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6166672 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:6166672 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:6166672 | pubmed:author | pubmed-author:ImaiKK | lld:pubmed |
| pubmed-article:6166672 | pubmed:author | pubmed-author:FerroneSS | lld:pubmed |
| pubmed-article:6166672 | pubmed:author | pubmed-author:GlassyM CMC | lld:pubmed |
| pubmed-article:6166672 | pubmed:author | pubmed-author:NgA KAK | lld:pubmed |
| pubmed-article:6166672 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6166672 | pubmed:volume | 127 | lld:pubmed |
| pubmed-article:6166672 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6166672 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6166672 | pubmed:pagination | 505-9 | lld:pubmed |
| pubmed-article:6166672 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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| pubmed-article:6166672 | pubmed:meshHeading | pubmed-meshheading:6166672-... | lld:pubmed |
| pubmed-article:6166672 | pubmed:year | 1981 | lld:pubmed |
| pubmed-article:6166672 | pubmed:articleTitle | Differential effect of interferon on the expression of tumor-associated antigens and histocompatibility antigens on human melanoma cells: relationship to susceptibility to immune lysis mediated by monoclonal antibodies. | lld:pubmed |
| pubmed-article:6166672 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6166672 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6166672 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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