| pubmed-article:6130806 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6130806 | lifeskim:mentions | umls-concept:C0999699 | lld:lifeskim |
| pubmed-article:6130806 | lifeskim:mentions | umls-concept:C0020885 | lld:lifeskim |
| pubmed-article:6130806 | lifeskim:mentions | umls-concept:C0019588 | lld:lifeskim |
| pubmed-article:6130806 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:6130806 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6130806 | pubmed:dateCreated | 1983-4-15 | lld:pubmed |
| pubmed-article:6130806 | pubmed:abstractText | 1 The possible temperature-dependent interconversion of histamine H1- and H2-receptors in the guinea-pig ileum suggested from previous studies was re-investigated by use of new and selective H2-receptor agonists and antagonists. 2 Chlorpheniramine, and H1-blocker, caused a rightward shift of the cumulative histamine dose-response curve at both 37 degrees C and 12 degrees C. Conversely cimetidine and tiotidine, two H2-receptor blockers, were ineffective at both temperatures. Metiamide behaved as a non competitive antagonist at 12 degrees C but only in very high concentrations. 3 Dimaprit and impromidine, two selective H2-receptor agonists, were inactive at both 37 degrees C and 12 degrees C when given alone, whereas at both temperatures they elicited the already described relaxation of the contractions induced by histamine. 4 Similar results were obtained on the guinea-pig whole ileum and on the longitudinal muscle strip: this indicates a lack of interference of the circular smooth muscle. 5 Our results allow us to conclude that no temperature-dependent interconversion of histamine H1- and H2-receptors occurs in the guinea-pig ileum. | lld:pubmed |
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| pubmed-article:6130806 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6130806 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6130806 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6130806 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:6130806 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6130806 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:6130806 | pubmed:issn | 0007-1188 | lld:pubmed |
| pubmed-article:6130806 | pubmed:author | pubmed-author:BertacciniGG | lld:pubmed |
| pubmed-article:6130806 | pubmed:author | pubmed-author:ZappiaLL | lld:pubmed |
| pubmed-article:6130806 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6130806 | pubmed:volume | 78 | lld:pubmed |
| pubmed-article:6130806 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6130806 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6130806 | pubmed:pagination | 11-6 | lld:pubmed |
| pubmed-article:6130806 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6130806 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6130806 | pubmed:articleTitle | Evidence against the temperature-dependent interconversion of histamine H1- and H2-receptors in the guinea-pig ileum. | lld:pubmed |
| pubmed-article:6130806 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6130806 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:6130806 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6130806 | lld:pubmed |
