pubmed-article:6126891 | pubmed:abstractText | Experiments were carried out with female tree-shrews (Tupaia belangeri). Following 6-hydroxydopamine injections into the ventral tegmental area, considerable variations in tyrosine-hydroxylase activity in the respective target regions of the A10 area occurred. Depletion of the THY-activity in the septum (SE), the entorhinal cortex (ECO), the frontal cortex and the basal ganglia correlated with an impairment in the performance of a passive avoidance task (indicated by testing 24 hours postshock). Partial correlation analysis revealed that the variations of THY-activity in the SE and ECO are primarily related to this failure in passive avoidance acquisition. | lld:pubmed |