pubmed-article:6121595 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6121595 | lifeskim:mentions | umls-concept:C0330390 | lld:lifeskim |
pubmed-article:6121595 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
pubmed-article:6121595 | lifeskim:mentions | umls-concept:C1522564 | lld:lifeskim |
pubmed-article:6121595 | lifeskim:mentions | umls-concept:C0029282 | lld:lifeskim |
pubmed-article:6121595 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
pubmed-article:6121595 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
pubmed-article:6121595 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
pubmed-article:6121595 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:6121595 | pubmed:dateCreated | 1982-6-21 | lld:pubmed |
pubmed-article:6121595 | pubmed:abstractText | The pharmacological characteristics of the myocardial adrenoceptor of the mouse have been examined during embryogenesis by measuring ornithine decarboxylase (ODC, EC 4.1.1.17) induction. 2 A four fold elevation of ODC activity was observed after isoprenaline (10 mg/kg, s.c.), and enzyme activity was increased two to three fold following adrenaline (1 mg/kg, s.c.) or terbutaline given by direct injection to the foetus (10 microgram/500 mg). 3 Pretreatment with the beta-adrenoceptor antagonist, propranolol (10 mg/kg), totally blocked the increase in ODC activity. 4 Elevation of myocardial ODC activity was not inhibited by metoprolol, a relatively specific beta-adrenoceptor antagonist, at a dose of 10 mg/kg. 5 Since the increase in ODC activity was blocked by a beta-adrenoceptor antagonist (propranolol) and enzyme activity was stimulated by terbutaline, a beta 2-agonist, we conclude that beta 2-adrenoceptors are selectively coupled to the regulation of murine cardiac ODC activity following catecholamine stimulation. | lld:pubmed |
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pubmed-article:6121595 | pubmed:language | eng | lld:pubmed |
pubmed-article:6121595 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6121595 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6121595 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:6121595 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6121595 | pubmed:month | Mar | lld:pubmed |
pubmed-article:6121595 | pubmed:issn | 0007-1188 | lld:pubmed |
pubmed-article:6121595 | pubmed:author | pubmed-author:RussellD HDH | lld:pubmed |
pubmed-article:6121595 | pubmed:author | pubmed-author:CopelandJ GJG | lld:pubmed |
pubmed-article:6121595 | pubmed:author | pubmed-author:RoeskeW RWR | lld:pubmed |
pubmed-article:6121595 | pubmed:author | pubmed-author:WombleJ RJR | lld:pubmed |
pubmed-article:6121595 | pubmed:author | pubmed-author:LarsonD FDF | lld:pubmed |
pubmed-article:6121595 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6121595 | pubmed:volume | 75 | lld:pubmed |
pubmed-article:6121595 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6121595 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6121595 | pubmed:pagination | 479-83 | lld:pubmed |
pubmed-article:6121595 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:6121595 | pubmed:meshHeading | pubmed-meshheading:6121595-... | lld:pubmed |
pubmed-article:6121595 | pubmed:year | 1982 | lld:pubmed |
pubmed-article:6121595 | pubmed:articleTitle | beta 2-Adrenoceptors regulate induction of myocardial ornithine decarboxylase in mice in vivo. | lld:pubmed |
pubmed-article:6121595 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6121595 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6121595 | lld:pubmed |