| pubmed-article:6117859 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6117859 | lifeskim:mentions | umls-concept:C0085080 | lld:lifeskim |
| pubmed-article:6117859 | lifeskim:mentions | umls-concept:C0683598 | lld:lifeskim |
| pubmed-article:6117859 | lifeskim:mentions | umls-concept:C1511657 | lld:lifeskim |
| pubmed-article:6117859 | lifeskim:mentions | umls-concept:C0105855 | lld:lifeskim |
| pubmed-article:6117859 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:6117859 | pubmed:dateCreated | 1982-1-28 | lld:pubmed |
| pubmed-article:6117859 | pubmed:abstractText | Cell lines that have high levels of resistance to beta-aspartylhydroxamate and elevated levels of asparagine synthetase activity were selected in two steps from Chinese hamster ovary cells. Resistance to beta-aspartylhydroxmate was transferred into sensitive cells by using total genomic DNA derived from the dominant two-step mutants. The surviving colonies were characterized as transferants on the basis of transfer frequency, degree of resistance to beta-aspartylhydroxamate, increased level of asparagine synthetase activity, expression of the donor form of asparagine synthetase, codominance in hybrids, and instability of the phenotype in the absence of selection. | lld:pubmed |
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| pubmed-article:6117859 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6117859 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6117859 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:6117859 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6117859 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:6117859 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:6117859 | pubmed:author | pubmed-author:SiminovitchLL | lld:pubmed |
| pubmed-article:6117859 | pubmed:author | pubmed-author:AndrulisI LIL | lld:pubmed |
| pubmed-article:6117859 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6117859 | pubmed:volume | 78 | lld:pubmed |
| pubmed-article:6117859 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6117859 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6117859 | pubmed:pagination | 5724-8 | lld:pubmed |
| pubmed-article:6117859 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6117859 | pubmed:meshHeading | pubmed-meshheading:6117859-... | lld:pubmed |
| pubmed-article:6117859 | pubmed:year | 1981 | lld:pubmed |
| pubmed-article:6117859 | pubmed:articleTitle | DNA-mediated gene transfer of beta-aspartylhydroxamate resistance into Chinese hamster ovary cells. | lld:pubmed |
| pubmed-article:6117859 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6117859 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6117859 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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