pubmed-article:6115692 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6115692 | lifeskim:mentions | umls-concept:C1524059 | lld:lifeskim |
pubmed-article:6115692 | lifeskim:mentions | umls-concept:C1280551 | lld:lifeskim |
pubmed-article:6115692 | lifeskim:mentions | umls-concept:C0003842 | lld:lifeskim |
pubmed-article:6115692 | lifeskim:mentions | umls-concept:C0031327 | lld:lifeskim |
pubmed-article:6115692 | lifeskim:mentions | umls-concept:C0019588 | lld:lifeskim |
pubmed-article:6115692 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
pubmed-article:6115692 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:6115692 | pubmed:dateCreated | 1981-11-22 | lld:pubmed |
pubmed-article:6115692 | pubmed:abstractText | 1 In helically-cut strips of dog coronary, superior mesenteric, right gastro-epiploic and renal arteries contracted with prostaglandin F2 alpha (PGF 2 alpha), histamine produced a dose-related relaxation, while, in contrast, the amine caused only a contraction of cerebral arterial strips. 2 The contractile response of cerebral arteries to histamine was attenuated by chlorpheniramine (10(-6)M) but was unaffected by cimetidine (10(-5)M). Relaxant responses to histamine of coronary and renal arteries were significantly attenuated by treatment with cimetidine and to a similar extent by combined treatment with cimetidine and chlorpheniramine. Chlorpheniramine alone was ineffective. 3 In mesenteric and gastro-epiploic arteries, relaxant responses to histamine were attenuated only slightly by cimetidine. Chlorpheniramine slowed the development of histamine-induced relaxations but did not alter the magnitude of the relaxations. Combined treatment with these H1- and H2- antagonists attenuated the histamine-induced relaxations to an appreciably greater extent than treatment with cimetidine alone. 4 It may be concluded that the cerebroarterial contraction induced by histamine is mediated through H1-receptors and the relaxations of coronary and renal arteries induced by histamine are mediated through H2-receptors. It appears that H1- and H2-receptors interact with each other to produce potentiation of histamine-induced relaxations of mesenteric and gastro-epiploic arteries. | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:language | eng | lld:pubmed |
pubmed-article:6115692 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6115692 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6115692 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6115692 | pubmed:month | Sep | lld:pubmed |
pubmed-article:6115692 | pubmed:issn | 0007-1188 | lld:pubmed |
pubmed-article:6115692 | pubmed:author | pubmed-author:ToddMM | lld:pubmed |
pubmed-article:6115692 | pubmed:author | pubmed-author:YamamotoMM | lld:pubmed |
pubmed-article:6115692 | pubmed:author | pubmed-author:KonishiMM | lld:pubmed |
pubmed-article:6115692 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6115692 | pubmed:volume | 74 | lld:pubmed |
pubmed-article:6115692 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6115692 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6115692 | pubmed:pagination | 111-8 | lld:pubmed |
pubmed-article:6115692 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:meshHeading | pubmed-meshheading:6115692-... | lld:pubmed |
pubmed-article:6115692 | pubmed:year | 1981 | lld:pubmed |
pubmed-article:6115692 | pubmed:articleTitle | Different mechanisms of action of histamine in isolated arteries of the dog. | lld:pubmed |
pubmed-article:6115692 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6115692 | pubmed:publicationType | In Vitro | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6115692 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6115692 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6115692 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6115692 | lld:pubmed |