pubmed-article:6106192 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6106192 | lifeskim:mentions | umls-concept:C0007600 | lld:lifeskim |
pubmed-article:6106192 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
pubmed-article:6106192 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:6106192 | lifeskim:mentions | umls-concept:C0242363 | lld:lifeskim |
pubmed-article:6106192 | lifeskim:mentions | umls-concept:C0524984 | lld:lifeskim |
pubmed-article:6106192 | lifeskim:mentions | umls-concept:C1704387 | lld:lifeskim |
pubmed-article:6106192 | lifeskim:mentions | umls-concept:C1522642 | lld:lifeskim |
pubmed-article:6106192 | lifeskim:mentions | umls-concept:C0443211 | lld:lifeskim |
pubmed-article:6106192 | lifeskim:mentions | umls-concept:C0549178 | lld:lifeskim |
pubmed-article:6106192 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:6106192 | pubmed:dateCreated | 1980-11-25 | lld:pubmed |
pubmed-article:6106192 | pubmed:abstractText | Continuous cell lines that secrete both insulin and somatostatin were established by two cooperating groups of investiagtors from a serially transplantable, radiation-induced, rat islet cell tumor. The cell lines, named RIN-r and RIN-m, were initiated from tumors maintained in inbred rats or in athymic nude mice, respectively. The cultured cells are epithelioid, free of fibroblast contamination, and can be cloned. They have a hypodiploid chromosome number, are tumorigenic, and posses amine-handling properties, including high levels of L-dopa decarboxylase and formaldehyde-induced fluorescence. Preliminary analysis of clones revealed a spectrum of insulin secretion from undetectable to relatively high. These clonal cell lines provide important systems to study the biology of insulin and somatostatin. | lld:pubmed |
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pubmed-article:6106192 | pubmed:language | eng | lld:pubmed |
pubmed-article:6106192 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6106192 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6106192 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6106192 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6106192 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6106192 | pubmed:month | Jun | lld:pubmed |
pubmed-article:6106192 | pubmed:issn | 0027-8424 | lld:pubmed |
pubmed-article:6106192 | pubmed:author | pubmed-author:WeirG CGC | lld:pubmed |
pubmed-article:6106192 | pubmed:author | pubmed-author:GazdarA FAF | lld:pubmed |
pubmed-article:6106192 | pubmed:author | pubmed-author:OieH KHK | lld:pubmed |
pubmed-article:6106192 | pubmed:author | pubmed-author:KingD LDL | lld:pubmed |
pubmed-article:6106192 | pubmed:author | pubmed-author:ChickW LWL | lld:pubmed |
pubmed-article:6106192 | pubmed:author | pubmed-author:LaurisVV | lld:pubmed |
pubmed-article:6106192 | pubmed:author | pubmed-author:SimsH LHL | lld:pubmed |
pubmed-article:6106192 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6106192 | pubmed:volume | 77 | lld:pubmed |
pubmed-article:6106192 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6106192 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6106192 | pubmed:pagination | 3519-23 | lld:pubmed |
pubmed-article:6106192 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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pubmed-article:6106192 | pubmed:year | 1980 | lld:pubmed |
pubmed-article:6106192 | pubmed:articleTitle | Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor. | lld:pubmed |
pubmed-article:6106192 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6106192 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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