pubmed-article:6103727 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6103727 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:6103727 | lifeskim:mentions | umls-concept:C0018787 | lld:lifeskim |
pubmed-article:6103727 | lifeskim:mentions | umls-concept:C0037993 | lld:lifeskim |
pubmed-article:6103727 | lifeskim:mentions | umls-concept:C0028351 | lld:lifeskim |
pubmed-article:6103727 | lifeskim:mentions | umls-concept:C0001645 | lld:lifeskim |
pubmed-article:6103727 | lifeskim:mentions | umls-concept:C0243127 | lld:lifeskim |
pubmed-article:6103727 | lifeskim:mentions | umls-concept:C1521828 | lld:lifeskim |
pubmed-article:6103727 | lifeskim:mentions | umls-concept:C0443331 | lld:lifeskim |
pubmed-article:6103727 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:6103727 | pubmed:dateCreated | 1980-8-15 | lld:pubmed |
pubmed-article:6103727 | pubmed:abstractText | 1 The effects of (+) and (+/-)-propranolol, pindolol, alprenolol, practolol, acebutolol and bretylium were studied on the turnover rate of noradrenaline in heart and spleen of rats. 2 Bretylium (8 mg/kg) greatly reduced the turnover rate of noradrenaline in both organs. 3 (+)-Propranolol (4 and 10 mg/kg) also diminished the turnover rate of noradrenaline, but its effects were smaller than those of (+/-)-propranolol (4 and 10 mg/kg). 4 Pindolol (300 micrograms/kg) greatly increased the turnover rate of noradrenaline; this effect was especially important in the spleen. 5 Alprenolol (4 and 10 mg/kg) acebutolol (20 and 40 mg/kg) practolol (10 mg/kg) did not produce any significant change. 6 These effects are compatible with the view that beta-adrenoceptor blocking agents may affect noradrenaline release in different manners: anaesthetic properties of some of these drugs and blockade of beta 2 prejunctional adrenoceptors produce a diminished release of transmitter, whereas the intrinsic sympathomimetic action of pindolol causes the opposite effect. | lld:pubmed |
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pubmed-article:6103727 | pubmed:language | eng | lld:pubmed |
pubmed-article:6103727 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6103727 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6103727 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6103727 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6103727 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6103727 | pubmed:month | May | lld:pubmed |
pubmed-article:6103727 | pubmed:issn | 0007-1188 | lld:pubmed |
pubmed-article:6103727 | pubmed:author | pubmed-author:AlexandreJ... | lld:pubmed |
pubmed-article:6103727 | pubmed:author | pubmed-author:ChevillardCC | lld:pubmed |
pubmed-article:6103727 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6103727 | pubmed:volume | 69 | lld:pubmed |
pubmed-article:6103727 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6103727 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6103727 | pubmed:pagination | 35-40 | lld:pubmed |
pubmed-article:6103727 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:6103727 | pubmed:year | 1980 | lld:pubmed |
pubmed-article:6103727 | pubmed:articleTitle | Influence of beta-adrenoceptor blocking agents on the turnover rate of cardiac and splenic noradrenaline in rats. | lld:pubmed |
pubmed-article:6103727 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6103727 | pubmed:publicationType | In Vitro | lld:pubmed |