| pubmed-article:6099281 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6099281 | lifeskim:mentions | umls-concept:C0205145 | lld:lifeskim |
| pubmed-article:6099281 | lifeskim:mentions | umls-concept:C0524637 | lld:lifeskim |
| pubmed-article:6099281 | lifeskim:mentions | umls-concept:C1523873 | lld:lifeskim |
| pubmed-article:6099281 | lifeskim:mentions | umls-concept:C0004745 | lld:lifeskim |
| pubmed-article:6099281 | lifeskim:mentions | umls-concept:C0016904 | lld:lifeskim |
| pubmed-article:6099281 | lifeskim:mentions | umls-concept:C0205923 | lld:lifeskim |
| pubmed-article:6099281 | lifeskim:mentions | umls-concept:C0076147 | lld:lifeskim |
| pubmed-article:6099281 | lifeskim:mentions | umls-concept:C0071048 | lld:lifeskim |
| pubmed-article:6099281 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:6099281 | pubmed:dateCreated | 1985-4-26 | lld:pubmed |
| pubmed-article:6099281 | pubmed:abstractText | The cage convulsant [35S]tert-butylbicyclophosphorothionate [( 35S]TBPS) labels a presumed sedative-convulsant receptor complex. The relative potencies of barbiturates in competing for [35S]TBPS binding parallels their potencies in enhancing benzodiazepine receptor binding. Barbiturates inhibit [35S]TBPS binding in a complex, mixed competitive fashion, leading to a decrease in both the apparent affinity of TBPS for its sites and the apparent number of TBPS sites. All of the barbiturates examined markedly accelerate the dissociation of [35S]TBPS from its recognition sites, while picrotoxinin does not affect the dissociation. These results suggest that the barbiturate and picrotoxinin/TBPS recognition sites are distinct but allosterically linked. | lld:pubmed |
| pubmed-article:6099281 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6099281 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6099281 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6099281 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6099281 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:6099281 | pubmed:issn | 0014-2999 | lld:pubmed |
| pubmed-article:6099281 | pubmed:author | pubmed-author:SnyderS HSH | lld:pubmed |
| pubmed-article:6099281 | pubmed:author | pubmed-author:SnowmanA MAM | lld:pubmed |
| pubmed-article:6099281 | pubmed:author | pubmed-author:TrifilettiR... | lld:pubmed |
| pubmed-article:6099281 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6099281 | pubmed:day | 13 | lld:pubmed |
| pubmed-article:6099281 | pubmed:volume | 106 | lld:pubmed |
| pubmed-article:6099281 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6099281 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6099281 | pubmed:pagination | 441-7 | lld:pubmed |
| pubmed-article:6099281 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:meshHeading | pubmed-meshheading:6099281-... | lld:pubmed |
| pubmed-article:6099281 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6099281 | pubmed:articleTitle | Barbiturate recognition site on the GABA/benzodiazepine receptor complex is distinct from the picrotoxinin/TBPS recognition site. | lld:pubmed |
| pubmed-article:6099281 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6099281 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:6099281 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6099281 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6099281 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6099281 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6099281 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6099281 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6099281 | lld:pubmed |
