pubmed-article:6088567 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6088567 | lifeskim:mentions | umls-concept:C0376325 | lld:lifeskim |
pubmed-article:6088567 | lifeskim:mentions | umls-concept:C0016055 | lld:lifeskim |
pubmed-article:6088567 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
pubmed-article:6088567 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:6088567 | pubmed:dateCreated | 1984-10-23 | lld:pubmed |
pubmed-article:6088567 | pubmed:abstractText | Human plasma fibronectin interacts with viruses. When fibronectin-containing human sera negative for antibodies to hepatitis A virus (HAV) were added to suspensions of HAV, radioimmunological detection of HAV was reduced. This masking effect seemed to depend on the fibronectin concentration of the sera: plasma fibronectin purified by cryoprecipitation and affinity chromatography showed a masking effect on purified HAV which was dependent on the concentrations of fibronectin and HAV. Fibronectin peptides were obtained by subtilisin digestion: the non-collagen-binding regions of the fibronectin molecule were involved in the binding of HAV. We conclude that fibronectin has a virus-binding activity which interferes with radioimmunological methods for virus detection, and may contribute to the frequent transmission of hepatitis viruses by blood products enriched in fibronectin. | lld:pubmed |
pubmed-article:6088567 | pubmed:language | eng | lld:pubmed |
pubmed-article:6088567 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6088567 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6088567 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6088567 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6088567 | pubmed:month | Jul | lld:pubmed |
pubmed-article:6088567 | pubmed:issn | 0166-0934 | lld:pubmed |
pubmed-article:6088567 | pubmed:author | pubmed-author:SahaT KTK | lld:pubmed |
pubmed-article:6088567 | pubmed:author | pubmed-author:LiehrHH | lld:pubmed |
pubmed-article:6088567 | pubmed:author | pubmed-author:MetzgerPP | lld:pubmed |
pubmed-article:6088567 | pubmed:author | pubmed-author:WaldherrRR | lld:pubmed |
pubmed-article:6088567 | pubmed:author | pubmed-author:SeeligH PHP | lld:pubmed |
pubmed-article:6088567 | pubmed:author | pubmed-author:SeeligRR | lld:pubmed |
pubmed-article:6088567 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6088567 | pubmed:volume | 8 | lld:pubmed |
pubmed-article:6088567 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6088567 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6088567 | pubmed:pagination | 335-47 | lld:pubmed |
pubmed-article:6088567 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:6088567 | pubmed:meshHeading | pubmed-meshheading:6088567-... | lld:pubmed |
pubmed-article:6088567 | pubmed:year | 1984 | lld:pubmed |
pubmed-article:6088567 | pubmed:articleTitle | Virus-binding activity of fibronectin: masking of hepatitis A virus. | lld:pubmed |
pubmed-article:6088567 | pubmed:publicationType | Journal Article | lld:pubmed |
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