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| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C0023516 | lld:lifeskim |
| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C0024369 | lld:lifeskim |
| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C1179435 | lld:lifeskim |
| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C0243042 | lld:lifeskim |
| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C1705248 | lld:lifeskim |
| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C0728938 | lld:lifeskim |
| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C1998793 | lld:lifeskim |
| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C1548799 | lld:lifeskim |
| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C1524073 | lld:lifeskim |
| pubmed-article:5926298 | lifeskim:mentions | umls-concept:C0449432 | lld:lifeskim |
| pubmed-article:5926298 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:5926298 | pubmed:dateCreated | 1967-2-5 | lld:pubmed |
| pubmed-article:5926298 | pubmed:abstractText | The mast cell-rupturing component present in the lysosomes of rabbit exudate PMN neutrophil leukocytes has been identified and some of its physical and chemical properties have been described. The active agent is a low molecular weight (1200 to 2400) polypeptide containing a relatively large proportion of the basic amino acid, arginine. It is thermostable and dialyzable, and does not cause contraction of the isolated guinea pig ileum. The mast cell-rupturing activity of the agent is destroyed by trypsin. A second permeability factor with a larger molecular weight is present in crude extracts of PMN granules. Although this substance does not lyse mast cells, it is capable of evoking delayed permeability responses in rabbit skin. | lld:pubmed |
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| pubmed-article:5926298 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:5926298 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:5926298 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:5926298 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:5926298 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:5926298 | pubmed:author | pubmed-author:JanoffAA | lld:pubmed |
| pubmed-article:5926298 | pubmed:author | pubmed-author:SeegersWW | lld:pubmed |
| pubmed-article:5926298 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:5926298 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:5926298 | pubmed:volume | 124 | lld:pubmed |
| pubmed-article:5926298 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:5926298 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:5926298 | pubmed:pagination | 833-49 | lld:pubmed |
| pubmed-article:5926298 | pubmed:dateRevised | 2010-6-22 | lld:pubmed |
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| pubmed-article:5926298 | pubmed:year | 1966 | lld:pubmed |
| pubmed-article:5926298 | pubmed:articleTitle | Mediators of inflammation in leukocyte lysosomes. VI. Partial purification and characterization of a mast cell-rupturing component. | lld:pubmed |
| pubmed-article:5926298 | pubmed:publicationType | Journal Article | lld:pubmed |
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